628-34-2 Usage
Description
2-Chloroethyl ethyl ether is an organic compound with the chemical formula ClCH2CH2OCH2CH3. It is a clear, colorless to slightly yellow liquid at room temperature and is commonly used as a pharmaceutical intermediate due to its versatile chemical properties.
Uses
Used in Pharmaceutical Industry:
2-Chloroethyl ethyl ether is used as a pharmaceutical intermediate for the synthesis of various drugs. Its unique chemical structure allows it to be a key component in the development of medications that target specific biological pathways.
Used in Photocatalytic Oxidation:
In the field of environmental chemistry, 2-Chloroethyl ethyl ether is utilized in photocatalytic oxidation processes. When 2-chloroethyl ethyl sulfide is exposed to TiO2 illuminated with UV light at 25 or 80°C in air, it undergoes progressive oxidation. This process yields primary intermediates such as ethylene, chloroethylene, ethanol, acetaldehyde, chloroacetaldehyde, diethyl disulfide, 2-chloroethyl ethyl disulfide, and bis(2-chloroethyl) disulfide. The final products of this reaction include water (H2O), carbon dioxide (CO2), sulfur dioxide (SO2), surface sulfate ions (SO42-), and hydrogen chloride (HCl), which are essential for understanding and managing the environmental impact of chemical reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 628-34-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 628-34:
(5*6)+(4*2)+(3*8)+(2*3)+(1*4)=72
72 % 10 = 2
So 628-34-2 is a valid CAS Registry Number.
InChI:InChI=1/C4H9ClO/c1-2-6-4-3-5/h2-4H2,1H3
628-34-2Relevant articles and documents
Muramatsu et al.
, p. 1155 (1969)
Trifluoromethylthiolation of 1,3-dithiane
Munavalli,Rohrbaugh,Szafraniec,Durst
, p. 305 - 324 (2008/02/04)
With a view to synthesize 2-(trifluoromethylthio)-1,3-dithiane (1), 1,3-dithiane (2) was reacted in dry pentane at -78°C under dry N2 with trifluoromethylsulfenyl chloride (3) and was found to furnish the desired compound in poor yields along with ten other compounds. Under similar conditions, 2-lithio-1,3-dithiane on treatment with 2 and bis-(trifluoromethyl) disulfide (4) gave 8.0% and 10.0% yields of 1, respectively. In connection with this study, (cholromethyl) propyl sulfide and bis(propylthio)methane were synthesized. The reaction of the latter with 3 was also investigated. The characterization of the primary compound formed in the reaction of 2 with 3 using the 'INAPT'-NMR and GC-MS, the probable mechanism of the formation of the various compounds and their mass spectral identification are presented in this article. Copyright Taylor & Francis Group, LLC.
Synthesis of 6,6'-diamino-2,2'-biquinoline and 2,2'-bi-1,6- naphthyridine
Janiak, Christoph,Deblon, Stephan,Uehlin, Lars
, p. 959 - 964 (2007/10/03)
High-yield synthesis and characterization of the new heterocycles 6,6'- diamino-2,2'-biquinoline (3), 6,6'-bis(N,N-dimethyl-amino)-2,2'-biquinoline (4), and 2,2'-bi-1,6-naphthyridine (5) are described. The preparation of 3 and 4 is based on the coupling of 2-amino-6-chloroquinoline and 2-chloro-6- dimethylaminoquinoline in the presence of NiCl2·6H2O/PPh3/Zn in DMF (NiCRA). Compound 5 was synthesized through a condensation reaction of 4- aminopyridine-3-carbaldehyde and butane-2,3-dione.
