628291-55-4Relevant articles and documents
Michael addition of activated nitriles to 4[(+)-camphor-10′-sulfonylamino]-acetophenone and some of its chalcones
El-Shehawy, Ashraf A.,Attia, Adel M. E.
, p. 1129 - 1142 (2007/10/03)
4-[(+)-Camphor-10′-sulfonylamino]acetophenone (2) and some of its chalcones 3 were easily prepared in quantitative yields starting from (+)-camphor-10-sulfonyl chloride. Several new 2-oxo-, 2-thio-, as well as 2-amino-pyridines carrying the camphor sulfonylamino group as a substituent were synthesized easily in one step by Michael addition of several activated nitriles to compounds 2 and 3. The synthesis of some fused pyridines also was investigated.