628734-36-1

Basic information

• Product Name: 3-benzyl-5-chloro-2-(2-dimethylamino-vinyl)-3H-pyrrolo[2,1-f][1,2,4]triazin-4-one
• Synonyms: 3-benzyl-5-chloro-2-(2-dimethylamino-vinyl)-3H-pyrrolo[2,1-f][1,2,4]triazin-4-one
• CAS NO: 628734-36-1
• Molecular Weight: 328.801
• Mol File: 628734-36-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-benzyl-5-chloro-2-(2-dimethylamino-vinyl)-3H-pyrrolo[2,1-f][1,2,4]triazin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-5-chloro-2-(2-dimethylamino-vinyl)-3H-pyrrolo[2,1-f][1,2,4]triazin-4-one(628734-36-1)
• EPA Substance Registry System: 3-benzyl-5-chloro-2-(2-dimethylamino-vinyl)-3H-pyrrolo[2,1-f][1,2,4]triazin-4-one(628734-36-1)

Safety Data

• Hazardous Substances Data: 628734-36-1(Hazardous Substances Data)

Upstream product

• 226410-00-0 3-chloro-1H-pyrrole-2-carboxylic acid methyl ester 
• 628734-34-9 5-chloro-2-methyl-3H-pyrrolo[2,1-f][1,2,4]triazin-4-oner 
• 753447-98-2 methyl 1-amino-3-chloro-1H-pyrrole-2-carboxylate 

Downstream Products

• 628734-37-2 3-benzyl-5-chloro-4-oxo-3,4-dihydro-pyrrolo[2,1-f][1,2,4]triazine-2-carbaldehyde 
• 906672-41-1 3-benzyl-5-chloro-2-(1-chloro-propyl)-3H-pyrrolo[2,1-f][1,2,4]triazin-4-one 
• 628733-98-2 (+/-)-N-(3-N-BOC-aminopropyl)-N-[1-(3-benzyl-5-chloro-4-oxo-3,4-dihydropyrrolo[2,1-f][1,2,4]triazine-2-yl)]propylamine 

Relevant articles and documents

Synthesis and SAR of pyrrolotriazine-4-one based Eg5 inhibitors

Synthesis and SAR of substituted pyrrolotriazine-4-one analogues as Eg5 inhibitors are described. Many of these analogues displayed potent inhibitory activities in the Eg5 ATPase and A2780 cell proliferation assays. In addition, pyrrolotriazine-4-one anal