62893-24-7 Usage
Description
(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid, also known as (αR)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxy-benzeneacetic Acid, is a white crystalline powder with chemical properties that make it a valuable intermediate in the pharmaceutical industry. It is characterized by its unique molecular structure, which includes a 4-ethyl-2,3-dioxopiperazine ring and a 4-hydroxyphenyl group, contributing to its potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid is used as an intermediate for the preparation of Cephalosporin derivatives. These derivatives exhibit potent antibacterial activities against both Gram-positive and Gram-negative bacteria, making them essential in the development of new antibiotics to combat drug-resistant infections.
Used in Drug Synthesis:
As a key intermediate, (2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid plays a crucial role in the synthesis of various pharmaceutical compounds. Its unique structure allows for the creation of new drugs with improved properties, such as enhanced efficacy, reduced side effects, and better pharmacokinetics.
Used in Research and Development:
(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid is also utilized in research and development for the study of its chemical properties, reactivity, and potential applications in drug design. Researchers can use this intermediate to explore new synthetic routes, develop novel drug candidates, and investigate its interactions with biological targets.
Check Digit Verification of cas no
The CAS Registry Mumber 62893-24-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,8,9 and 3 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 62893-24:
(7*6)+(6*2)+(5*8)+(4*9)+(3*3)+(2*2)+(1*4)=147
147 % 10 = 7
So 62893-24-7 is a valid CAS Registry Number.
InChI:InChI=1/C15H17N3O6/c1-2-17-7-8-18(13(21)12(17)20)15(24)16-11(14(22)23)9-3-5-10(19)6-4-9/h3-6,11,19H,2,7-8H2,1H3,(H,16,24)(H,22,23)/p-1/t11-/m1/s1
62893-24-7Relevant articles and documents
A D (-)-α - (4-ethyl -2,3-dioxygen piperazin-1-carboxamido) method for the preparation of acetic acid the hydroxybenzotriazole
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Paragraph 0030; 0039; 0040, (2017/01/31)
The invention discloses a method for preparing D(-)-alpha-(4-ethyl-2,3-dioxopiperazine-1-formamido) p-hydoxyphenylacetic acid. 4-ethyl-2,3-dioxopiperazine-1-formate and a salt of D(-)-alpha-p-hydoxyphenylglycine are subjected to a condensation reaction in an aqueous phase to obtain the D(-)-alpha-(4-ethyl-2,3-dioxopiperazine-1-formamido) p-hydoxyphenylacetic acid. The 4-ethyl-2,3-dioxopiperazine-1-formate is used as a raw material, zinc halide is used as a catalyst, and the aqueous phase reaction is adopted, so that the process is compact and environment-friendly, the intermediate EOCP is easy to separate, the use of organic solvents is completely avoided, the working environment is improved, the post treatment cost is saved, the treatment cost of 'three wastes' is greatly reduced, the purity of the obtained HO-EPCP is high, the purity of the one-step crystallized product is more than 96%, re-crystallization is not needed, and the economic and social benefits are significant.