62935-72-2 Usage
Description
7-Methoxycoumarin-4-acetic acid is an organic compound that serves as a key intermediate in the synthesis of coumarin-based fluorescent reagents. It possesses unique chemical properties that make it a valuable component in various applications, particularly in the development of fluorescence probes for chromatographic detection and as a precursor for the creation of novel fluorescent derivatives.
Uses
Used in Fluorescent Reagent Synthesis:
7-Methoxycoumarin-4-acetic acid is used as a precursor for the synthesis of coumarin-type fluorescent reagents. Its role in the production of these reagents is crucial, as it contributes to the development of compounds with enhanced fluorescence properties, which are essential for various analytical techniques.
Used in Chromatographic Detection:
In the field of chromatographic detection, 7-Methoxycoumarin-4-acetic acid is utilized as a key intermediate for the synthesis of fluorescence probes. These probes are vital for the identification and quantification of specific molecules in complex samples, improving the sensitivity and accuracy of the detection process.
Used in Pharmaceutical Research:
7-Methoxycoumarin-4-acetic acid has been employed in the preparation of two novel LysB29 selectively labeled fluorescent derivatives of human insulin. This application highlights its potential in pharmaceutical research, where it can contribute to the development of innovative drugs and therapies.
Used in Peptide Synthesis:
7-Methoxycoumarin-4-acetic acid also serves as a fluorescent label for peptides, which is particularly useful in the synthesis of cell-penetrating peptide transportan 10 (tp10). This application demonstrates its versatility in peptide synthesis, allowing for the creation of molecules with specific properties and functions.
Check Digit Verification of cas no
The CAS Registry Mumber 62935-72-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,9,3 and 5 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 62935-72:
(7*6)+(6*2)+(5*9)+(4*3)+(3*5)+(2*7)+(1*2)=142
142 % 10 = 2
So 62935-72-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H10O5/c1-16-8-2-3-9-7(4-11(13)14)5-12(15)17-10(9)6-8/h2-3,5-6H,4H2,1H3,(H,13,14)
62935-72-2Relevant articles and documents
-
Laskowski,Clinton
, p. 3987,3989 (1950)
-
Synthesis of 2-(2-oxo-2H-chromen-4-yl)acetamides as potent acetylcholinesterase inhibitors and molecular insights into binding interactions
Kara, Jiraporn,Suwanhom, Paptawan,Wattanapiromsakul, Chatchai,Nualnoi, Teerapat,Puripattanavong, Jindaporn,Khongkow, Pasarat,Lee, Vannajan Sanghiran,Gaurav, Anand,Lomlim, Luelak
, (2019/07/08)
Sixteen novel coumarin-based compounds are reported as potent acetylcholinesterase (AChE) inhibitors. The most active compound in this series, 5a (IC50 0.04 ± 0.01 μM), noncompetitively inhibited AChE with a higher potency than tacrine and gala
Synthetic and Structural Studies on Novel 4,3′-Bicoumarins
Pujar, Kiran K.,Kulkarni, Manohar V.,Alawandi, Ganesh N.,Anilkumar,Basanagouda, Mahantesha
, p. 2043 - 2052 (2015/08/18)
A series of directly linked 4-3′ bicoumarins have been synthesized by both Knoevenagel and Perkin reactions. This single-step transformation was accomplished by the reaction of coumarin-4-acetates with substituted salicylaldehydes in presence of piperidin
