6299-37-2 Usage
Description
1,3,5-tris(2-chloroethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione, also known as Tretamine, is a pharmaceutical antineoplastic agent used in the treatment of various types of cancer. It is a triazine derivative and an alkylating agent that works by attaching alkyl groups to DNA, thereby damaging it and preventing cancer cells from growing and multiplying.
Used in Pharmaceutical Industry:
1,3,5-tris(2-chloroethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione is used as an antineoplastic agent for the treatment of various types of cancer, including ovarian and breast cancer. It is administered intravenously and is often used in combination with other chemotherapy drugs to enhance the treatment's effectiveness.
Due to its potency and potential toxic effects, Tretamine is only used under the supervision of a qualified healthcare professional to ensure safe and effective treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 6299-37-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,9 and 9 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 6299-37:
(6*6)+(5*2)+(4*9)+(3*9)+(2*3)+(1*7)=122
122 % 10 = 2
So 6299-37-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H12Cl3N3O3/c10-1-4-13-7(16)14(5-2-11)9(18)15(6-3-12)8(13)17/h1-6H2
6299-37-2Relevant articles and documents
Synthesis and biological evaluation of novel cyanuric acid-tethered tris-pyridinium derivatives
Derkach, Yana V.,Detusheva, Elena V.,Egorov, Mikhail P.,Frolov, Nikita A.,Minaeva, Alexandra P.,Vereshchagin, Anatoly N.
, p. 368 - 369 (2021)
Novel tris(4-alkylaminopyridin-1-ium) trichlorides with alkylcyanuric spacer were synthesized by quaternization of 4-alkylaminopyridines with tris(2-chloroethyl) cyanurate. The obtained compounds were evaluated for microbiological activity against five pathogenic bacterial strains (Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Acinobacter baumannii, Pseudomonas aeruginosa). The results indicate the presence of pronounced antibacterial properties in this group of compounds.