6299-92-9 Usage
Description
1H-Benzimidazol-1-amine(9CI) is a chemical compound with the molecular formula C7H8N2. It is a derivative of benzimidazole, containing an amine group attached to the first carbon atom of the benzimidazole ring. This versatile chemical is commonly used as a building block in organic synthesis and pharmaceutical research.
Uses
Used in Pharmaceutical Research:
1H-Benzimidazol-1-amine(9CI) is used as a key intermediate in the synthesis of various pharmaceutical compounds for its potential applications in the development of drugs targeting different biological pathways.
Used in Anticancer Applications:
1H-Benzimidazol-1-amine(9CI) is used as a potential anticancer agent, as it has been studied for its ability to target and inhibit the growth of cancer cells.
Used in Antiviral Applications:
1H-Benzimidazol-1-amine(9CI) is used as a potential antiviral agent, as it has been studied for its ability to inhibit viral replication and reduce the severity of viral infections.
Used in Antifungal Applications:
1H-Benzimidazol-1-amine(9CI) is used as a potential antifungal agent, as it has been studied for its ability to inhibit the growth of fungi and treat fungal infections.
Used in Organic Synthesis:
1H-Benzimidazol-1-amine(9CI) is used as a versatile building block in organic synthesis, enabling the creation of a wide range of chemical compounds for various scientific and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 6299-92-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,9 and 9 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 6299-92:
(6*6)+(5*2)+(4*9)+(3*9)+(2*9)+(1*2)=129
129 % 10 = 9
So 6299-92-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H7N3/c8-10-5-9-6-3-1-2-4-7(6)10/h1-5H,8H2
6299-92-9Relevant articles and documents
Electrochemical reduction of o-nitrophenylhydrazides into 1,2,4-benzotriazines.
Chibani, A.,Hazard, R.,Tallec, A.
, p. 343 - 352 (2007/10/02)
Phenylhydroxylamines, obtained in aqueous medium, by electroreduction of o-nitrophenylhydrazides (o-NO2-C6H4-NH-NHCOR), undergo a disproportionation reaction leading finally to the corresponding o-amino compound; the latter partially rearranges into an o-amidophenylhydrazine (o-RCONH-C6H4-NH-NH2).In a basic media, the disproportionation reaction is concurrent with a ring closure of the intermediate hydroxylamine giving rise to a 1,2,4-benzotriazine.The latter is also obtained by anodic oxidation of the amine, mixed with anilide resulting from the hydrazine oxidation.Electroreduction, immediately followed by an anodic oxidation gives rise to about 50percent yield in the expected triazine.In an acidic media, disproportionation is faster, but the resulting amine undergoes a ring closure reaction into dihydrobenzotriazine when R = H or CH3.Subsequent oxidation of the latter gives rise to 75percent yield of the triazine, mixed with N-aminobenzimidazole resulting from the hydrazine.When R = Ph, the amine is stable but only very poor yields of triazine are obtained by anodic oxidation; the major evolution is probably the formation of an unstable benzoylbenzotriazole.Key words: cyclic voltammetry, controlled potential reduction and oxidation, 1,2,4-benzotriazine, 1-amino-2-alkylbenzimidazoles, organic electrosynthesis.
