6300-04-5

Basic information

• Product Name: 3-(Dimethylamino)propanoicacid
• Synonyms: beta.-Alanine,N,N-dimethyl;N,N-dimethyl-.beta.-Alanine;b-Alanine, N,N-diMethyl-;3-(N,N-Dimethylamino)propionic acid;NSC 45506;NSC 73153
• CAS NO: 6300-04-5
• Molecular Formula: C₅H₁₁NO₂
• Molecular Weight: 117.15
• Mol File: 6300-04-5.mol
• Article Data: 1

Chemical Properties

• Melting Point: 143-146℃
• Boiling Point: 140-142 °C(Press: 0.15 Torr)
• Appearance: /
• Density: 1.037
• PKA: 3.67±0.14(Predicted)
• CAS DataBase Reference: 3-(Dimethylamino)propanoicacid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(Dimethylamino)propanoicacid(6300-04-5)
• EPA Substance Registry System: 3-(Dimethylamino)propanoicacid(6300-04-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 6300-04-5(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 73, p. 3168, 1951 DOI: 10.1021/ja01151a050

InChI:InChI=1S/C5H11NO2/c1-6(2)4-3-5(7)8/h3-4H2,1-2H3,(H,7,8)

Upstream product

• 62131-47-9 4-chlorophenyl 3,3-dimethylaminopropionate 
• 62131-49-1 4-methylphenyl 3,3-dimethylaminopropionate 
• 62131-48-0 phenyl 3,3-dimethylaminopropionate 

Downstream Products

• 63132-39-8 olpadronate 
• 17321-77-6 clomipramine hydrochloride 
• 1225-65-6 Prothipendyl hydrochloride 
• 53-60-1 promazine Hydrochloride 
• 1433890-27-7 C₃₁H₃₁N₅O₃ 
• 17268-47-2 3-(N,N-dimethylamino)-N',N'-dimethylpropionamide 
• 2680-03-7 N,N-Dimethylacrylamide 
• 1185996-35-3 N-(3-(2-((2-(3,4-dimethoxyphenyl)ethyl)amino)pyrimidin-4-yl)phenyl)-N3,N3-dimethyl-β-alaninamide 
• 1111085-99-4 CBD bis(3-(dimethylamino)propionate) 

Relevant articles and documents

Ester Saponification in Dipolar Aprotic Solvents: Role of Solvent-Solute Ground State Interactions

The rates of hydrolysis of the aryl esters of 3-aminopropionates and phenyl 3-morpholinopropionate have been measured in aqueous ethanol and aqueous DMSO solvent media.The magnitude of rate acceleration in aq.DMSO as compared to aq. ethanolis much lower for above esters than that observed for aryl benzoates.The reduced rate acceleration in aq.DMSO is due to the solvation of the ground state of the ester by DMSO by interaction of the lone pair on the nitrogen of the ester with the DMSO dipole.