6301-72-0

Basic information

• Product Name: 1,3-benzodioxol-5-ylmethanediyl diacetate
• CAS NO: 6301-72-0
• Molecular Formula: C₁₂H₁₂O₆
• Molecular Weight: 252.2201
• Mol File: 6301-72-0.mol
• Article Data: 29

Chemical Properties

• Boiling Point: 354.8°C at 760 mmHg
• Flash Point: 157.1°C
• Density: 1.322g/cm³
• Vapor Pressure: 3.27E-05mmHg at 25°C
• Refractive Index: 1.535
• CAS DataBase Reference: 1,3-benzodioxol-5-ylmethanediyl diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-benzodioxol-5-ylmethanediyl diacetate(6301-72-0)
• EPA Substance Registry System: 1,3-benzodioxol-5-ylmethanediyl diacetate(6301-72-0)

Safety Data

• Hazardous Substances Data: 6301-72-0(Hazardous Substances Data)

Usage

Chemical compound

1,3-benzodioxol-5-ylmethanediyl diacetate

Psychoactive drug

Yes

Effects

Stimulant and hallucinogenic

Recreational use

Common

Mechanism of action

Increases levels of neurotransmitters (serotonin, dopamine, norepinephrine) in the brain

Resulting feelings

Euphoria, increased energy, enhanced sensory perception

Legal status

Illegal in many countries due to potential for abuse and harmful health effects

Health risks

Increased body temperature, dehydration, potential long-term adverse effects on the brain

Clinical trials

Shown promise in treating psychiatric conditions such as post-traumatic stress disorder (PTSD) and anxiety

Upstream product

• 59259-90-4 5-(dimethoxymethyl)benzo[d][1,3]dioxole 
• 108-24-7 acetic anhydride 
• 120-57-0 piperonal 

Downstream Products

• 120-57-0 piperonal 

Relevant articles and documents

Solvent-free catalytic preparation of 1,1-diacetates using a silica-supported functional ionic liquid as catalyst

An efficient and convenient preparation of acylals from aldehydes and acetic anhydride, under solvent-free conditions, in the presence of a silica-supported functional ionic liquid, Si-[SbSipim][PF6], is reported. Si-[SbSipim][PF6] acts as a catalyst and can be recovered and reused four times without apparent loss of its catalytic activity.

A convenient and efficient protocol for the synthesis of acylals catalyzed by Br?nsted acidic ionic liquids under ultrasonic irradiation

The synthesis of acylals (1,1-diacetates) via the reactions of aldehydes with acetic anhydride was carried out in 85-97% yields at room temperature under ultrasound irradiation catalyzed by the Br?nsted acidic ionic liquid [bmpy]HSO4. This method provides several advantages, such as solvent-free conditions, operational simplicity, higher yields, and reduced environmental consequences. The ionic liquid was recovered and reused.

Silica phosphoric acid: An efficient and recyclable catalyst for the solvent-free synthesis of acylals and their deprotection in MeOH

Silica phosphoric acid was used as an efficient, mild, and recyclable solid catalyst for the synthesis of acylals from various structurally diverse aldehydes and acetic anhydride under solvent-free conditions. The acylation of aldehydes was highly chemoselective, and no ketone was acylated, which provided a method for the synthesis of acylals from aldehydes in the presence of ketones. Silica phosphoric acid-catalyzed deprotection of acylals to the corresponding aldehydes in MeOH has also been developed with excellent yield. The deprotection of the acylals of aromatic aldehydes took priority over those of aliphatic aldehydes. Copyright Taylor & Francis Group, LLC.