Cas 630116-07-3,2-(4-(pyridin-2-yl)-piperazin-1-yl)-N-(3-methylphenyl)acetamide

630116-07-3

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Basic information

Product Name: 2-(4-(pyridin-2-yl)-piperazin-1-yl)-N-(3-methylphenyl)acetamide
Synonyms: 2-(4-(pyridin-2-yl)-piperazin-1-yl)-N-(3-methylphenyl)acetamide
CAS NO:630116-07-3
Molecular Formula:
Molecular Weight: 310.399
EINECS: N/A
Product Categories: N/A
Mol File: 630116-07-3.mol
Article Data: 5

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 2-(4-(pyridin-2-yl)-piperazin-1-yl)-N-(3-methylphenyl)acetamide(CAS DataBase Reference)
NIST Chemistry Reference: 2-(4-(pyridin-2-yl)-piperazin-1-yl)-N-(3-methylphenyl)acetamide(630116-07-3)
EPA Substance Registry System: 2-(4-(pyridin-2-yl)-piperazin-1-yl)-N-(3-methylphenyl)acetamide(630116-07-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 630116-07-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 630116-07-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,3,0,1,1 and 6 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 630116-07:
(8*6)+(7*3)+(6*0)+(5*1)+(4*1)+(3*6)+(2*0)+(1*7)=103
103 % 10 = 3
So 630116-07-3 is a valid CAS Registry Number.

630116-07-3Upstream product

630116-07-3Downstream Products

630116-07-3Relevant articles and documents

Dopamine D4 Receptor-Selective Compounds Reveal Structure-Activity Relationships that Engender Agonist Efficacy

Keck, Thomas M.,Free, R. Benjamin,Day, Marilyn M.,Brown, Sonvia L.,Maddaluna, Michele S.,Fountain, Griffin,Cooper, Charles,Fallon, Brooke,Holmes, Matthew,Stang, Christopher T.,Burkhardt, Russell,Bonifazi, Alessandro,Ellenberger, Michael P.,Newman, Amy H.,Sibley, David R.,Wu, Chun,Boateng, Comfort A.

, p. 3722 - 3740 (2019)

The dopamine D4 receptor (D4R) plays important roles in cognition, attention, and decision making. Novel D4R-selective ligands have promise in medication development for neuropsychiatric conditions, including Alzheimer's d

Synthesis and functional activity of (2-aryl-1-piperazinyl)-N-(3- methylphenyl)acetamides: Selective dopamine D4 receptor agonists

Matulenko, Mark A.,Hakeem, Ahmed A.,Kolasa, Teodozyi,Nakane, Masaki,Terranova, Marc A.,Uchic, Marie E.,Miller, Loan N.,Chang, Renjie,Donnelly-Roberts, Diana L.,Namovic, Marian T.,Moreland, Robert B.,Brioni, Jorge D.,Stewart, Andrew O.

, p. 3471 - 3483 (2007/10/03)

Diaryl piperazine acetamides were identified as potent and selective dopamine D4 receptor agonists. Our strategy is based on an amide bond reversal of an acid sensitive, dopamine D4 receptor partial agonist, PD 168077. This reversal provided compounds with excellent potency and improved stability. Systematic evaluation of the substitution on the aryl piperazine portion revealed a significant effect on functional activity. The synthesis and biological activity of these new dopamine D4 agonists is discussed.

Acetamides and benzamides that are useful in treating sexual dysfunction

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Page 42, (2010/02/06)

The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.

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