630129-08-7

Basic information

• Product Name: (1S,2S)-2-N-benzyl-1-(2'-furyl)-1-O-(tert-butyldimethylsilyl)-2-phenylethane
• CAS NO: 630129-08-7
• Molecular Weight: 407.628
• Mol File: 630129-08-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S,2S)-2-N-benzyl-1-(2'-furyl)-1-O-(tert-butyldimethylsilyl)-2-phenylethane(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2S)-2-N-benzyl-1-(2'-furyl)-1-O-(tert-butyldimethylsilyl)-2-phenylethane(630129-08-7)
• EPA Substance Registry System: (1S,2S)-2-N-benzyl-1-(2'-furyl)-1-O-(tert-butyldimethylsilyl)-2-phenylethane(630129-08-7)

Safety Data

• Hazardous Substances Data: 630129-08-7(Hazardous Substances Data)

Upstream product

• 139765-20-1 (S)-2-(tert-butyldimethylsilyloxy)-2-(furan-2-yl)acetonitrile 
• 10017-07-9 (S)-2-(2'-furyl)-2-hydroxy-acetonitrile 
• 98-01-1 furfural 

Downstream Products

• 630129-17-8 (1S,2S)-2-N-acryloyl-2-N-benzyl-1-(2'-furyl)-2-phenyl-1-O-(tert-butyldimethylsilyl)ethane 

Relevant articles and documents

Stereochemistry of intramolecular Diels-Alder furan (IMDAF) reactions of furyl-substituted chiral ethanolamides

This paper describes the stereoselective outcome of the intramolecular Diels-Alder furan (IMDAF) reaction of substituted (2S,3S)-ethanolamides 9-13, which were synthesised from a furyl substituted cyanohydrin. The latter was obtained from 2-furaldehyde with high enantioselectivity by an oxynitrilase catalysed addition of hydrogen cyanide. The stereochemistry of the IMDAF products was shown to be dependent on the size of the ethanolamide substituents R. Small substituents (H, Me, CN) gave exclusively axo-cycloaddition, whereas more bulky ones (Ph, Et) gave both exo- and endo-addition, the larger phenyl substituent giving a high endo-exo-ratio.