6303-43-1 Usage
General Description
6-chloro-N^4^-methyl-N^4^-phenylpyrimidine-2,4-diamine is a chemical compound that belongs to the class of pyrimidine derivatives. It is a crystalline, solid substance that is commonly used in the pharmaceutical industry. 6-chloro-N~4~-methyl-N~4~-phenylpyrimidine-2,4-diamine has potential pharmacological applications, especially as an antineoplastic and antiviral agent. It works by interfering with the synthesis of nucleic acids, which inhibits the growth of cancer cells and viruses. Additionally, it has been studied for its potential use in the treatment of various types of cancer, including breast and lung cancer. Its chemical structure and properties make it a promising candidate for further research and development in the field of medicine and pharmacology.
Check Digit Verification of cas no
The CAS Registry Mumber 6303-43-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,0 and 3 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 6303-43:
(6*6)+(5*3)+(4*0)+(3*3)+(2*4)+(1*3)=71
71 % 10 = 1
So 6303-43-1 is a valid CAS Registry Number.
6303-43-1Relevant articles and documents
CHEMICAL COMPOUNDS
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Page/Page column 147-148, (2010/11/04)
The invention is directed to to substituted indazole derivatives. Specifically, the invention is directed to compounds according to Formula I: wherein R1 - R6 and X are defined herein. The compounds of the invention are inhibitors of PDK1 and can be useful in the treatment of disorders characterized by constitutively activated ACG kinases such as cancer and more specifically leukemia and cancers of the breast, colon, and lung. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting PDK1 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.