6304-56-9

Basic information

• Product Name: 1-CYCLOHEXYL-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID
• Synonyms: TIMTEC-BB SBB011264;1-CYCLOHEXYL-5-OXO-3-PYRROLIDINECARBOXYLIC ACID;1-CYCLOHEXYL-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID;1-cyclohexyl-5-oxopyrrolidine-3-carboxylic acid(SALTDATA: FREE);1-cyclohexyl-5-keto-pyrrolidine-3-carboxylic acid;3-Pyrrolidinecarboxylic acid, 1-cyclohexyl-5-oxo-
• CAS NO: 6304-56-9
• Molecular Formula: C₁₁H₁₇NO₃
• Molecular Weight: 211.26
• Mol File: 6304-56-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 422.9°C at 760 mmHg
• Flash Point: 209.5°C
• Appearance: /
• Vapor Pressure: 2.46E-08mmHg at 25°C
• CAS DataBase Reference: 1-CYCLOHEXYL-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CYCLOHEXYL-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID(6304-56-9)
• EPA Substance Registry System: 1-CYCLOHEXYL-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID(6304-56-9)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 6304-56-9(Hazardous Substances Data)

Usage

General Description

1-CYCLOHEXYL-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID, also known as L-proline, is a naturally occurring amino acid. It is an essential component of the human diet and is involved in the synthesis of proteins and enzymes. L-proline is also a key building block for collagen, the most abundant protein in the human body and an important structural component of connective tissues, skin, and bones. Additionally, L-proline has been studied for its potential health benefits, including its role in supporting cardiovascular health and promoting healthy skin and joint function. It is commonly used as a dietary supplement and is found in a variety of foods, including meat, dairy, and legumes.

InChI:InChI=1/C11H17NO3/c13-10-6-8(11(14)15)7-12(10)9-4-2-1-3-5-9/h8-9H,1-7H2,(H,14,15)/p-1/t8-/m1/s1

Upstream product

• 97-65-4 2-methylenesuccinic acid 
• 108-91-8 cyclohexylamine 

Downstream Products

• 1181577-49-0 1-cyclohexyl-5-oxo-pyrrolidine-3-carbonyl chloride 
• 886615-26-5 1-cyclohexyl-4-(hydroxymethyl)pyrrolidin-2-one 

Relevant articles and documents

Synthesis and biological activity of 1-alkyl(heteryl)-5-oxopyrrolidine-3-carboxylic acids

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INDOLE AMIDE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES

This invention provides novel compounds and the novel compounds for use as a medicine, more in particular for the prevention or treatment of neurodegenerative disorders, more specifically certain neurological disorders, such as disorders collectively known as tauopathies, and disorders characterised by cytotoxic α-synuclein amyloidogenesis. The present invention also relates to the use of said novel compounds for the manufacture of medicaments useful for treating such neurodegenerative disorders. The present invention further relates to pharmaceutical compositions including said novel compounds and to methods for the preparation of said novel compounds.

Pyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis

In view of the worldwide spread of multidrug resistance of Mycobacterium tuberculosis, there is an urgent need to discover antituberculosis agent with novel structures. InhA, the enoyl acyl carrier protein reductase (ENR) from M. tuberculosis, is one of t