631090-57-8Relevant articles and documents
Synthesis and cytotoxicity of novel 20-O-linked homocamptothecin ester derivatives as potent topoisomerase I inhibitors
Li, Di-Zao,Wang, Cun-Ying,Liu, Rui-Hua,Wang, Yan-Ming,Ji, Teng-Fei,Li, Yu-Rong,Pan, Xian-Dao
, p. 1179 - 1188 (2014/01/06)
In an attempt to improve the antitumor activity of homocamptothecins (hCPTs), a series of novel 20-O-linked hCPT ester derivatives were first designed and synthesized based on a synthetic route, by which hCPTs are acylated with different substituted pheno