6312-53-4 Usage
Description
2,3-Dihydro-5-hydroxy-1,4-naphthoquinone, also known as plumbagin, is a natural chemical compound derived from the roots of the Plumbago rosea plant. It is a naphthoquinone derivative characterized by its antioxidant and anti-inflammatory properties. Plumbagin has been the subject of research for its potential therapeutic effects, particularly as an anti-cancer agent, and has also demonstrated antimicrobial, antimalarial, and neuroprotective activities, as well as promise in diabetes treatment.
Uses
Used in Pharmaceutical Industry:
2,3-Dihydro-5-hydroxy-1,4-naphthoquinone is used as a therapeutic agent for its potential anti-cancer properties, with studies indicating its effectiveness against various types of cancer. It is also being explored for its antimicrobial and antimalarial activities, which could lead to the development of new treatments for infectious diseases.
Used in Neurodegenerative Disorder Treatment:
In the field of neurology, 2,3-Dihydro-5-hydroxy-1,4-naphthoquinone is used as a neuroprotective agent due to its potential to treat neurodegenerative disorders. Its antioxidant properties may help mitigate the effects of oxidative stress associated with such conditions.
Used in Diabetes Management:
2,3-Dihydro-5-hydroxy-1,4-naphthoquinone is used as a potential treatment for diabetes, with research suggesting it may help manage blood sugar levels and improve overall metabolic health.
While the potential applications of 2,3-Dihydro-5-hydroxy-1,4-naphthoquinone are promising, it is important to note that further research is necessary to fully understand its mechanisms of action and to establish its safety and efficacy in various therapeutic contexts.
Check Digit Verification of cas no
The CAS Registry Mumber 6312-53-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,1 and 2 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 6312-53:
(6*6)+(5*3)+(4*1)+(3*2)+(2*5)+(1*3)=74
74 % 10 = 4
So 6312-53-4 is a valid CAS Registry Number.
InChI:InChI=1/C22H21FN2O4S/c1-4-28-19-12-15(11-17-20(26)24(2)22(30)25(3)21(17)27)7-10-18(19)29-13-14-5-8-16(23)9-6-14/h5-12H,4,13H2,1-3H3
6312-53-4Relevant articles and documents
STUDIES ON QUINONES. VI. ACID CATALIZED REARRANGEMENTS IN SOME 4-ACETYL-2,3-DIHYDROBENZOFURANS
Barrios, Luis,Ruiz, V. Manuel,Tapia, Ricardo,Valderrama, Jaime,Vega, Juan C.
, p. 187 - 190 (2007/10/02)
The reaction of 2-acetyl- and 5-acetyl-2-methoxy-1,4-benzoquinone (1a, 1c) with N-propenylpiperidine gave the corresponding 2,3-dihydrobenzofurans, 2b and 2c, containing the acetyl group at C-4.Acid treatment of these dihydrofurans rearranged to 8-methyl- and 2-methoxy-8-methyljuglone (4a, 4b).Juglone (4c) and 2,3-dihydrojuglone (6) were obtained in fair yields from 4-acetyl-2,5-dihydroxy-2,3-dihydrobenzofuran (2e).
