6315-51-1

Basic information

• Product Name: 2-DIPHENYLAMINO-ETHANOL
• Synonyms: 2-DIPHENYLAMINO-ETHANOL;Nsc21083;Ethanol, 2-(diphenylaMino)-
• CAS NO: 6315-51-1
• Molecular Formula: C₁₄H₁₅NO
• Molecular Weight: 213.275
• EINECS: 228-646-0
• Mol File: 6315-51-1.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 365.1°C at 760 mmHg
• Flash Point: 187.1°C
• Appearance: /
• Density: 1.134g/cm³
• Vapor Pressure: 5.68E-06mmHg at 25°C
• Refractive Index: 1.625
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-DIPHENYLAMINO-ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-DIPHENYLAMINO-ETHANOL(6315-51-1)
• EPA Substance Registry System: 2-DIPHENYLAMINO-ETHANOL(6315-51-1)

Safety Data

• Hazardous Substances Data: 6315-51-1(Hazardous Substances Data)

Usage

General Description

2-DIPHENYLAMINO-ETHANOL, also known as diphenylaminoethanol or DPAE, is a chemical compound with the molecular formula C14H15NO. It is a colorless to pale yellow liquid that is soluble in organic solvents such as ethanol and ether. DPAE is commonly used as a key intermediate in the synthesis of dyes and pigments, as well as in the manufacturing of pharmaceuticals and agrochemicals. It is also used as a stabilizer in plastics and as an additive in lubricants. DPAE is known for its ability to react with various organic compounds, making it a versatile compound in the chemical industry. It is important to handle DPAE with care as it may cause irritation to the skin, eyes, and respiratory system.

InChI:InChI=1/C14H15NO/c16-12-11-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10,16H,11-12H2

Upstream product

• 75-21-8 oxirane 
• 122-39-4 diphenylamine 
• 141-43-5 ethanolamine 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 87-72-9 D-Xylose 
• 1523440-95-0 2-(4-(diphenylamino)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane) 
• 540-51-2 2-bromoethanol 
• 28899-97-0 triphenylbismuth(V) diacetate 
• 107-07-3 2-chloro-ethanol 

Downstream Products

• 136059-31-9 1-chloro-4-(2-(diphenylamino)ethoxy)butane 
• 93007-91-1 diphenyl-(2-vinyloxy-ethyl)-amine 

Relevant articles and documents

Aza-Matteson Reactions via Controlled Mono-and Double-Methylene Insertions into Nitrogen-Boron Bonds

Boron-homologation reactions represent an efficient and programmable approach to prepare alkylboronates, which are valuable and versatile synthetic intermediates. The typical boron-homologation reaction, also known as the Matteson reaction, involves formal carbenoid insertions into C-B bonds. Here we report the development of aza-Matteson reactions via carbenoid insertions into the N-B bonds of aminoboranes. By changing the leaving groups of the carbenoids and altering Lewis acid activators, selective mono- and double-methylene insertions can be realized to access various α- and β-boron-substituted tertiary amines, respectively, from common secondary amines. The derivatization of complex amine-containing bioactive molecules, diverse functionalization of the boronate products, and sequential insertions of different carbenoids have also been achieved.

Facile N-arylation of amines and sulfonamides and O-arylation of phenols and arenecarboxylic acids

An efficient, transition-metal-free procedure for the N-arylation of amines, sulfonamides, and carbamates and O-arylation of phenols and carboxylic acids has been achieved by allowing these substrates to react with a variety of o-silylaryl inflates in the presence of CsF. Good to excellent yields of arylated products are obtained under very mild reaction conditions. This chemistry readily tolerates a variety of functional groups.

Method of treating filariae

The present invention relates to a novel method for treating a mammal suffering from filariae.