63213-42-3

Basic information

• Product Name: 4-(3,4-DIETHOXY-PHENYL)-4-OXO-BUTYRIC ACID
• Synonyms: 4-(3,4-Diethoxyphenyl)-4-oxobutanoic acid; 4-(3,4-Diethoxy-phenyl)-4-oxo-butyric acid; benzenebutanoic acid, 3,4-diethoxy-gamma-oxo-
• CAS NO: 63213-42-3
• Molecular Formula: C₁₄H₁₈O₅
• Molecular Weight: 266.29
• Mol File: 63213-42-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 450.7°C at 760 mmHg
• Flash Point: 168°C
• Appearance: /
• Density: 1.159g/cm³
• Vapor Pressure: 6.52E-09mmHg at 25°C
• Refractive Index: 1.519
• CAS DataBase Reference: 4-(3,4-DIETHOXY-PHENYL)-4-OXO-BUTYRIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3,4-DIETHOXY-PHENYL)-4-OXO-BUTYRIC ACID(63213-42-3)
• EPA Substance Registry System: 4-(3,4-DIETHOXY-PHENYL)-4-OXO-BUTYRIC ACID(63213-42-3)

Safety Data

• Hazardous Substances Data: 63213-42-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H18O5/c1-3-18-12-7-5-10(9-13(12)19-4-2)11(15)6-8-14(16)17/h5,7,9H,3-4,6,8H2,1-2H3,(H,16,17)

Upstream product

• 108-30-5 succinic acid anhydride 
• 2050-46-6 1,2-diethoxybenzene 

Downstream Products

• 137013-01-5 4-(3,4-diethoxyphenyl)butyric acid 
• 1240636-85-4 C₂₇H₂₉NO₄ 
• 1240636-84-3 C₂₉H₃₃NO₄ 
• 1240636-89-8 N-(4,5-diphenyl-1,3-thiazol-2-yl)-4-(3,4-diethoxyphenyl)-4-oxobutanamide 
• 1240636-87-6 C₂₃H₂₄N₂O₄S 
• 905590-61-6 N-(5-benzyl-4-phenyl-1,3-thiazol-2-yl)-4-(3,4-diethoxyphenyl)-4-oxobutanamide 
• 137376-72-8 2-Dimethylaminomethyl-6,7-diethoxy-3,4-dihydro-2H-naphthalen-1-one; hydrochloride 
• 905591-32-4 N-(7-bromo-4-phenylquinolin-2-yl)-4-(3,4-diethoxyphenyl)-4-oxobutanamdie 
• 905591-03-9 N-[5-(4-bromobenzyl)-4-phenyl-2-thienyl]-4-(3,4-diethoxyphenyl)-4-oxobutanamide 
• 905590-73-0 4-(3,4-diethoxyphenyl)-N-{4-[4-(methoxymethoxy)phenyl]quinolin-2-yl}-4-oxobutanamide 

Relevant articles and documents

AMIDE COMPOUND

The present invention relate to a compound represented by the formula (I) or (II) wherein ring A is an optionally substituted ring (the ring should not be pyrrolidine, piperidine and piperazine), ring B is an optionally substituted aromatic ring, ring D is an optionally substituted ring, R1 and R2 are each independently a hydrogen atom or a substituent, R3 is a hydrogen atom or a C1-6 alkyl group, or R3 is bonded to ring A to form a non-aromatic ring, ring Aa is an optionally substituted aromatic hydrocarbon, Y is CH or N, Ra1 is an optionally substituted hydrocarbon group, and Ra2 and Ra3 are each independently a hydrogen atom or a substituent, or a salt thereof. The present invention provides a compound having a DGAT inhibitory activity, which is useful for the treatment or amelioration of diseases or pathologies caused by high expression or high activation of DGAT.

SYNTHESIS OF 1,2-(DIMETHYLAMINOMETHYL-1-OXOPOLYMETHYLENE)BENZENES AND THEIR 4,5-DIETHOXY DERIVATIVES AND THEIR ANTI-INFLAMMATORY ACTIVITY

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