632327-19-6

Basic information

• Product Name: 3-(3-CHLORO-PHENYL)-3-OXO-PROPIONIC ACID METHYL ESTER
• Synonyms: 3-(3-CHLORO-PHENYL)-3-OXO-PROPIONIC ACID METHYL ESTER;3-CHLORO-BETA-OXO-BENZENEPROPANOIC ACID METHYL ESTER;Methyl 3-(3-chlorophenyl)-3-oxopropanoate;3-Chloro-b-oxo-benzenepropanoic acid Methyl ester
• CAS NO: 632327-19-6
• Molecular Formula: C₁₀H₉ClO₃
• Molecular Weight: 212.63
• Mol File: 632327-19-6.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 106-107°C/0.45mm
• Appearance: /
• Density: 1 +-.0.06 g/cm3(Predicted)
• PKA: 9.89±0.46(Predicted)
• CAS DataBase Reference: 3-(3-CHLORO-PHENYL)-3-OXO-PROPIONIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-CHLORO-PHENYL)-3-OXO-PROPIONIC ACID METHYL ESTER(632327-19-6)
• EPA Substance Registry System: 3-(3-CHLORO-PHENYL)-3-OXO-PROPIONIC ACID METHYL ESTER(632327-19-6)

Safety Data

• Hazardous Substances Data: 632327-19-6(Hazardous Substances Data)

Usage

General Description

3-(3-chloro-phenyl)-3-oxo-propionic acid methyl ester is a chemical compound with the molecular formula C11H11ClO3. It is a methyl ester of 3-(3-chlorophenyl)-3-oxo-propionic acid, and is also known by the chemical name 3-(3-chlorophenyl)-3-oxopropionic acid methyl ester. 3-(3-CHLORO-PHENYL)-3-OXO-PROPIONIC ACID METHYL ESTER is used in organic synthesis and chemical research, and it may also have potential applications in pharmaceuticals and agrochemicals. Its chlorophenyl group is likely to confer specific reactivity and properties that make it of interest for certain chemical reactions or applications. However,

Upstream product

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Downstream Products

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• 51699-45-7 (S)-(-)-1-(3'-Chlorophenyl)-1,3-Propanediol 
• 632327-23-2 (R)-(+)-methyl 3-(acetyloxy)-3-(3-chlorophenyl)propanoate 
• 879492-91-8 methyl 3-(acetyloxy)-3-(3-chlorophenyl)propanoate 
• 632327-21-0 methyl (S)-3-(3'-Chlorophenyl)-3-Hydroxypropionate 
• 51699-40-2 3-(3-chlorophenyl)-3-hydroxypropionic acid ethyl ester 
• 1372793-77-5 trans-methyl 3-(3-chlorophenyl)-3-(methoxyimino)propanoate 
• 1359872-86-8 C₁₂H₁₁ClO₃ 
• 1359872-62-0 1-(3-chlorobenzoyl)cyclopropanecarboxylic acid 
• 1204586-19-5 methyl 2-acetamido-3-(3-chlorophenyl)-3-oxopropanoate 
• 1279090-55-9 C₉H₉ClO₂ 
• 1245606-57-8 (Z)-1-(3-chlorophenyl)-3-methoxy-3-oxoprop-1-en-1-amine hydrochloride 
• 1242162-65-7 methyl 2-(3-chlorobenzoyl)pent-4-ynoate 

Relevant articles and documents

Discovery of Nonpungent Transient Receptor Potential Vanilloid 1 (TRPV1) Agonist as Strong Topical Analgesic

Paradoxically, some TRPV1 agonists are, at the organismal level, both nonpungent and clinically useful as topical analgesics. Here, we describe the scaled-up synthesis and characterization in mouse models of a novel, nonpungent vanilloid. Potent analgesic activity was observed in models of neuropathic pain, and the compound blocked capsaicin induced allodynia, showing dermal accumulation with little transdermal absorption. Finally, it displayed much weaker systemic toxicity compared to capsaicin and was negative in assays of genotoxicity.

PHENANTHROLINE PHOSPHONIC ACID DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

The present invention relates to a novel phenanthroline phosphonic acid compound and a pharmaceutical salt thereof, as well as an application of the compound and the pharmaceutical salt thereof as collagen prolyl hydroxylase inhibitors in the preparation of drugs for preventing or treating collagen prolyl-4-hydroxylase related disease.

SUBSTITUTED OXAZOLE- AND THIAZOLE-BASED CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS II

The invention relates to oxazole and thiazole-based carboxamide and urea derivatives as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.