63250-09-9

Basic information

• Product Name: 2,3-DINOR THROMBOXANE B2
• Synonyms: 2,3-DINOR-TXB2;2,3-DINOR THROMBOXANE B2;9ALPHA,11,15S-TRIHYDROXY-2,3-DINOR-THROMBA-5Z,13E-DIEN-1-OIC ACID;(E)-5-[(2S,3S,4S)-4,6-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]oxan-3-yl]pent-3-enoic acid;(5Z,13E,15S)-9α,11,15-Trihydroxy-2,3-dinorthromboxa-5,13-dien-1-oic acid;2,3-dinor Thromboxane B2 Lipid Maps MS Standard;RJHNVFKNIJQTQF-LMIBIYGPSA-N
• CAS NO: 63250-09-9
• Molecular Formula: C18H30O6
• Molecular Weight: 342.43
• Mol File: 63250-09-9.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 566.9°C at 760 mmHg
• Flash Point: 199.5°C
• Appearance: /
• Density: 1.209g/cm³
• Vapor Pressure: 3.25E-15mmHg at 25°C
• Refractive Index: 1.571
• CAS DataBase Reference: 2,3-DINOR THROMBOXANE B2(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DINOR THROMBOXANE B2(63250-09-9)
• EPA Substance Registry System: 2,3-DINOR THROMBOXANE B2(63250-09-9)

Safety Data

• Hazardous Substances Data: 63250-09-9(Hazardous Substances Data)

Usage

Description

2,3-DINOR THROMBOXANE B2, also known as 2,3-dinor TXB2, is a significant urinary metabolite of Thromboxane B2 (TXB2). It is released in substantial quantities from aggregating platelets and is metabolized during circulation to 11-dehydro TXB2. As an abundant urinary metabolite, 2,3-dinor TXB2 serves as a reliable marker for in vivo TXA2 synthesis. In healthy male volunteers, the median excretion of 2,3-dinor TXB2 is 10.3 ng/hour (138 pg/mg creatine).

Uses

Used in Medical Research:
2,3-DINOR THROMBOXANE B2 is used as a biomarker for [application reason] to monitor and assess in vivo TXA2 synthesis. This is particularly important in understanding platelet aggregation and related physiological processes.
Used in Pharmaceutical Industry:
2,3-DINOR THROMBOXANE B2 is used as a research tool for [application reason] in the development of drugs targeting platelet aggregation and related conditions. Its role as a biomarker allows for the evaluation of drug efficacy and potential therapeutic effects on TXA2 synthesis.
Used in Diagnostics:
2,3-DINOR THROMBOXANE B2 is used as a diagnostic indicator for [application reason] in identifying and monitoring conditions related to platelet aggregation and TXA2 synthesis. This can be particularly useful in the assessment of cardiovascular and thrombotic disorders.
Used in Clinical Trials:
2,3-DINOR THROMBOXANE B2 is used as an endpoint measurement for [application reason] in clinical trials evaluating the effects of new drugs or therapies on platelet aggregation and TXA2 synthesis. Its role as a biomarker provides a quantifiable and reliable method for assessing treatment outcomes.

InChI:InChI=1/C18H30O6/c1-2-3-4-7-13(19)10-11-16-14(8-5-6-9-17(21)22)15(20)12-18(23)24-16/h5-6,10-11,13-16,18-20,23H,2-4,7-9,12H2,1H3,(H,21,22)/b6-5-,11-10+/t13-,14?,15-,16+,18+/m0/s1