63307-62-0

Basic information

• Product Name: 1-hydroxy-1H-benzotriazole, ammonium salt
• Synonyms: 1-hydroxy-1H-benzotriazole, ammonium salt;HOBtsalts;Varioussaltsof1-HOBt,25%solutione.g.ammoniasalt;AMMONIUM1-HYDROXYBENZOTRIAZOLE;Ammonium1H-benzo[d][1,2,3]triazol-1-olate
• CAS NO: 63307-62-0
• Molecular Formula: C6H8N4O
• Molecular Weight: 152.15392
• EINECS: 264-090-5
• Mol File: 63307-62-0.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-hydroxy-1H-benzotriazole, ammonium salt(CAS DataBase Reference)
• NIST Chemistry Reference: 1-hydroxy-1H-benzotriazole, ammonium salt(63307-62-0)
• EPA Substance Registry System: 1-hydroxy-1H-benzotriazole, ammonium salt(63307-62-0)

Safety Data

• Safety Statements: x and NH3." target="_blank">Low toxicity by ingestion. A skin and eye irritant. When heated to decomposition it emits toxic vapo
• Hazardous Substances Data: 63307-62-0(Hazardous Substances Data)

Usage

General Description

1-hydroxy-1H-benzotriazole, ammonium salt is a chemical compound that is often used as an additive in various industrial processes, especially in the production of plastics and coatings. It is commonly used as a corrosion inhibitor, helping to protect metal surfaces from rust and deterioration. Additionally, it has been found to be effective in stabilizing the color and properties of dyes and pigments. This chemical is also used in the manufacturing of adhesives, rubber products, and water treatment chemicals. Its ability to act as a versatile and effective additive in a wide range of industrial applications makes it a valuable chemical in various manufacturing processes.

Upstream product

• 2592-95-2 benzotriazol-1-ol 

Relevant articles and documents

Synthesis of Enantiomerically Pure 5-Substituted Piperazine-2-Acetic Acid Esters as Intermediates for Library Production

The piperazine heterocycle is housed within a large number of FDA-approved drugs and biological probe compounds. Structurally, however, these compounds are mostly confined to substitutions on the two ring nitrogen atoms, rationalizing the expansion of piperazine chemical diversity through carbon substitutions. On the basis of the concept of systematic chemical diversity, a divergent six-step synthesis was developed in which chiral amino acids were transformed, with high diastereoselectivity, into either cis or trans 5-substituted piperazine-2-acetic acid esters that could be chromatographically rendered diastereomerically homogeneous. Starting from six commercially available amino acids or their respective amino alcohols (both antipodes), we obtained a complete set of 24 protected chiral 2,5-disubstituted piperazines, as single stereoisomers in multigram quantities. These diverse and versatile piperazines can be functionalized on either nitrogen atom, allowing them to be used as starting materials for parallel library synthesis and as intermediates for the targeted production of more complex C-substituted piperazine compounds.

Novel Receptor Antagonists and Their Methods of Use

The present invention relates to novel oxo-prolinamide derivatives of formula (I) which modulate P2X7 receptor function and are capable of antagonizing the effects of ATP at the P2X7 receptor and the use of such compounds or pharmaceutical compositions thereof in the treatment of disorders mediated by the P2X7 receptor, for example pain, inflammation and neurodegeneration.

NOVEL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS

The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such peptides as well as methods of using them to treat disorders associated with the HCV protease.