63321-54-0Relevant articles and documents
Structure-reactivity relationships as probes for the inhibition mechanism of cholesterol esterase by aryl carbamates. I. Steady-state kinetics
Lin, Gialih,Lai, Cheng-Yue,Liao, Wei-Cheng,Kuo, Bing-Hong,Lu, Chun-Ping
, p. 489 - 500 (2007/10/03)
For substituted phenyl-N-butyl carbamates (1) and 4-nitrophenyl-N-substituted carbamates (2), linear relationships between values of NH proton chemical shift (δNH), pKa, and logk[OH] and Hammett substituent constant (σ) or Taft subst
Linear free energy relationships of the inhibition of pancreatic cholesterol esterase by 4-nitrophenyl-N-alkylcarbamate
Lin, Gialih,Lai, Cheng-Yue
, p. 193 - 196 (2007/10/02)
4-Nitrophenyl-N-alkylcarbamates (1) as active site-directed irreversible inhibitors of pancreatic cholesterol esterase are investigated for values of the dissociation constant (K(i)), the carbamylation constant (k2), and the bimolecular rate co