633312-78-4Relevant articles and documents
The synthesis and structure-activity relationship of 4-benzimidazolyl- piperidinylcarbonyl-piperidine analogs as histamine H3 antagonists
Ting, Pauline C.,Lee, Joe F.,Albanese, Margaret M.,Wu, Jie,Aslanian, Robert,Favreau, Leonard,Nardo, Cymbelene,Korfmacher, Walter A.,West, Robert E.,Williams, Shirley M.,Anthes, John C.,Rivelli, Maria A.,Corboz, Michel R.,Hey, John A.
scheme or table, p. 5004 - 5008 (2010/10/05)
A structure-activity relationship study of the lead piperazinylcarbonylpiperidine compound 3 resulted in the identification of 4-benzimidazolyl-piperidinylcarbonyl-piperidine 6h as a histamine-3 (H 3) receptor antagonist. Additional optimizatio