633318-46-4

Basic information

• Product Name: 3,5-Dibromo-4-chloro-2,6-dimethylpyridine
• Synonyms: 3,5-Dibromo-4-chloro-2,6-dimethylpyridine
• CAS NO: 633318-46-4
• Molecular Formula: C7H6Br2ClN
• Molecular Weight: 299.39024
• Mol File: 633318-46-4.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 282.6±35.0 °C(Predicted)
• Appearance: /
• Density: 1.876±0.06 g/cm3(Predicted)
• PKA: 2.35±0.10(Predicted)
• CAS DataBase Reference: 3,5-Dibromo-4-chloro-2,6-dimethylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Dibromo-4-chloro-2,6-dimethylpyridine(633318-46-4)
• EPA Substance Registry System: 3,5-Dibromo-4-chloro-2,6-dimethylpyridine(633318-46-4)

Safety Data

• Hazardous Substances Data: 633318-46-4(Hazardous Substances Data)

Usage

General Description

3,5-Dibromo-4-chloro-2,6-dimethylpyridine is a chemical compound with the molecular formula C7H6Br2ClN. It is a substituted pyridine derivative with three halogen atoms attached to the pyridine ring. 3,5-Dibromo-4-chloro-2,6-dimethylpyridine is commonly used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It possesses a strong electron-withdrawing character due to the presence of the bromine and chlorine atoms, making it a valuable building block in organic chemistry. Additionally, it is also used as an intermediate in the production of insecticides and herbicides. Due to its unique structural features and chemical properties, 3,5-Dibromo-4-chloro-2,6-dimethylpyridine has applications in various fields such as medicinal chemistry and crop protection.

Upstream product

• 4563-28-4 3,5-dibromo-2,6-dimethylpyridin-4-ol 
• 13603-44-6 2,6-dimethylpyridin-4-ol 

Relevant articles and documents

PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION

Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS. (I)

5-(N-[6,5]-FUSED BICYCLIC ARYL TETRAHYDROISOQUINOLIN-6-YL) PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION

Disclosed are compounds of Formula (I), including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.

5-(N-BENZYL TETRAHYDROISOQUINOLIN-6-YL) PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION

Disclosed are compounds of Formula (I), including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS. In the compounds of formula (I), R1 is selected from hydrogen, alkyl, or cycloalkyi; R2 is selected from tetrahydroisoquinolinyl and is substituted with 1 R6 substituent and also with 0-3 halo or alkyl substituents; R3 is selected from azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, morpholinyl, homopiperidinyl, homopiperazinyl, or homomorpholinyl, and is substituted with 0-3 substituents selected from cyano, halo, alkyl, haloalkyi, alkoxy, and haloalkoxy; R4 is selected from alkyl or haloalkyi; R5 is alkyl; R6 is selected from Ar1, (Ar1)alkyl, (chromanyl)alkyl, cyanocycloalkyl or (dihydrobenzodioxinyl)alkyl; and Ar1 is phenyl substituted with 0-5 substituents selected from cyano, halo, alkyl, cycloalkyi, haloalkyi, hydroxy, alkoxy, haloalkoxy, (hydroxy)alkoxy, (alkoxy)alkoxy, phenoxy, benzyloxy, carboxy, phenyl, and cyanocycloalkyl.