633327-10-3

Basic information

• Product Name: 2,4-Difluoro-5-formylbenzonitrile
• Synonyms: 2,4-Difluoro-5-formylbenzonitrile
• CAS NO: 633327-10-3
• Molecular Formula: C₈H₃F₂NO
• Molecular Weight: 167.1123264
• Mol File: 633327-10-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 213.8±35.0 °C(Predicted)
• Appearance: /
• Density: 1.35±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2,4-Difluoro-5-formylbenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Difluoro-5-formylbenzonitrile(633327-10-3)
• EPA Substance Registry System: 2,4-Difluoro-5-formylbenzonitrile(633327-10-3)

Safety Data

• Hazardous Substances Data: 633327-10-3(Hazardous Substances Data)

Usage

General Description

2,4-Difluoro-5-formylbenzonitrile is a chemical compound with the molecular formula C8H3F2NO. It is a pale yellow solid that is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 2,4-Difluoro-5-formylbenzonitrile has two fluorine atoms and a nitrile group attached to a benzene ring, as well as a formyl group bonded to the benzene ring. It is a versatile building block in organic synthesis and can undergo various chemical reactions to produce a range of different compounds. Due to its reactivity and potential applications in drug discovery and development, 2,4-Difluoro-5-formylbenzonitrile is of interest to researchers and industries in the fields of pharmaceuticals and agrochemicals.

Upstream product

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• 333447-42-0 1,5-difluoro-2-iodo-4-methylbenzene 
• 473416-91-0 5-bromo-2,4-difluorobenzaldehyde 
• 544-92-3 copper(I) cyanide 

Relevant articles and documents

2. 4 - difluoro - 5 - (phthalazinone - 1 - methyl) - benzoyl piperazine compound and use thereof

The invention relates to a 2,4-difluoro-5-(phthalazone-1-methyl)-benzoyl piperazine compound and application of the 2,4-difluoro-5-(phthalazone-1-methyl)-benzoyl piperazine compound. Specifically, the invention discloses a compound of the structure shown in the formula I, wherein the definition of the compound of the structure shown in the formula I can be seen in the specification. The compound has the excellent PARP activity inhibitory effect and the excellent antitumor effect.

PYRAZOLE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME

The present invention provides a novel compound having an excellent JNK inhibitory effect. That is, it provides a compound represented by the following formula, a salt thereof or a hydrate of them. Wherein R1 designates -(CO)h-(NRa)j-(CRb=CRc)k-Ar (wherein Ra, Rb and Rc each independently designate a hydrogen atom, a halogen atom, hydroxyl group, an optionally substituted C1-6 alkyl group or the like; Cy designates a 5- or 6-membered heteroaryl; and V each independently designate the formula -L-X-Y (wherein L designates a single bond, an optionally substituted C1-6 alkylene group or the like; X designates a single bond or the formula -A- (wherein A designates NR2, O, CO, S, SO or SO2) and so on; and Y designates a hydrogen atom, a halogen atom, nitro group or the like).