6335-15-5

Basic information

• Product Name: bis(2-chlorophenyl)methanol
• CAS NO: 6335-15-5
• Molecular Formula: C₁₃H₁₀Cl₂O
• Molecular Weight: 253.1239
• Mol File: 6335-15-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 370.2°C at 760 mmHg
• Flash Point: 141.6°C
• Density: 1.325g/cm³
• Vapor Pressure: 3.89E-06mmHg at 25°C
• Refractive Index: 1.617
• CAS DataBase Reference: bis(2-chlorophenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: bis(2-chlorophenyl)methanol(6335-15-5)
• EPA Substance Registry System: bis(2-chlorophenyl)methanol(6335-15-5)

Safety Data

• Hazardous Substances Data: 6335-15-5(Hazardous Substances Data)

Usage

General Description

Bis(2-chlorophenyl)methanol, also known as triclosan, is a white crystalline powder with a slightly aromatic odor. It is commonly used as an antimicrobial agent in personal care products, such as toothpaste, soaps, and detergents. Triclosan has been widely used due to its effectiveness in preventing the growth of bacteria, fungi, and mold. However, it has also been the subject of controversy due to its potential negative effects on human health and the environment. Studies have shown that triclosan may disrupt hormone function, contribute to antibiotic resistance, and harm aquatic ecosystems. As a result, there has been increasing scrutiny and regulation of products containing triclosan, and many manufacturers have sought alternatives to this chemical.

Upstream product

• 694-80-4 2-bromo-1-chlorobenzene 
• 89-98-5 2-chloro-benzaldehyde 
• 615-41-8 2-iodochlorobenzene 
• 5293-97-0 2,2'-dichlorobenzophenone 
• 36692-27-0 2-chlorophenylmagnesium bromide 

Downstream Products

• 791119-72-7 1-benzyl-4-(2,2'-dichlorobenzhydryloxy)piperidine 
• 720674-03-3 C₂₆H₁₈Cl₄O 
• 439094-10-7 bis-(2-chlorophenyl)methylamine 
• 200868-49-1 bis-(2-chlorophenyl)-bromomethane 
• 109395-72-4 2,2'-dichloro-benzophenone-(2,4-dinitro-phenylhydrazone) 
• 7498-78-4 acetic acid-(2,2'-dichloro-benzhydryl ester) 
• 5293-97-0 2,2'-dichlorobenzophenone 

Relevant articles and documents

Synthesis, Structure, Reactivity, and Catalytic Activity of Cyclometalated (Phosphine)- and (Phosphinite)ruthenium Complexes

Reactions of naphthyl- and o-methylphenyl-substituted phosphines with [RuCl2(p-cymene)]2 resulted in the corresponding phosphine-substituted ruthenium dichlorides (1a,b and 3). When the reactions of aryl-substituted phosphines or pho

3 -MONOSUBSTITUTED TROPANE DERIVATIVES AS NOCICEPTIN RECEPTOR LIGANDS

Compounds of the formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 is aryl, arylalkyl, heteroaryl, heteroarylalkyl, cycloalkyl, cycloalkylalkyl, heterocycloalkyl, heterocycloalkylalkyl or alkyl, all optionally substituted; R

AZETIDINECARBOXAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CB1 RECEPTOR MEDIATED DISORDRS

Compounds of formula (I) and their use in therapy, particularly for the treatment of a disorder mediated by CB1 receptors, such as obesity, wherein: R1 is aryl or heteroaryl; R2 is alkyl, aryl or heteroaryl; R3 is alkyl, aryl, heteroaryl, NR9R10, OR 15, or NR16C(O)R17;Y is C=O, C=S, SO2, or (CR7R8)p; m = 1 or 2; n = 1 or 2; and p=1,2,3 or 4, R7 to R17 being as defined in the specification; wherein if -Y-R3 is -C(O)NH(alkyl) then: R1 and/or R2 is selected from heteroary1; and/or m and/or n is 2; and/or R11 and/or R12 is lower alkyl, or a pharmaceutically acceptable salt or prodrug thereof.