63364-56-7

Basic information

• Product Name: Cyclopropanecarboxylic acid, 1-amino-2-ethyl-, (1R,2R)-rel- (9CI)
• Synonyms: Cyclopropanecarboxylic acid, 1-amino-2-ethyl-, (1R,2R)-rel- (9CI)
• CAS NO: 63364-56-7
• Molecular Formula: C₆H₁₁NO₂
• Molecular Weight: 129.15704
• Product Categories: AMINOACID
• Mol File: 63364-56-7.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclopropanecarboxylic acid, 1-amino-2-ethyl-, (1R,2R)-rel- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanecarboxylic acid, 1-amino-2-ethyl-, (1R,2R)-rel- (9CI)(63364-56-7)
• EPA Substance Registry System: Cyclopropanecarboxylic acid, 1-amino-2-ethyl-, (1R,2R)-rel- (9CI)(63364-56-7)

Safety Data

• Hazardous Substances Data: 63364-56-7(Hazardous Substances Data)

Upstream product

• 88950-66-7 (1RS,2SR)-1-[(tert-butoxycarbonyl)amino]-2-ethylcyclopropane-1-carboxylic acid 
• 18795-92-1 1,1-dimethyl 2-ethylcyclopropane-1,1-dicarboxylate 
• 97935-31-4 2-ethylcyclopropane-1,1-dicarboxylic acid di-tert-butyl ester 
• 97935-34-7 Potassium; (1R,2S)-2-ethyl-1-methoxycarbonyl-cyclopropanecarboxylate 
• 138457-95-1 (1S,2S)-1-Amino-2-ethyl-cyclopropanecarboxylic acid methyl ester 
• 134639-29-5 C₁₆H₂₃NO₂ 
• 87429-74-1 3-Azido-4-ethyl-4,5-dihydro-3H-pyrazole-3-carboxylic acid methyl ester 
• 81852-62-2 Methyl (Z)-2-azido-pentenoate 
• 87429-76-3 1-Azido-2-ethyl-cyclopropanecarboxylic acid 

Downstream Products

• 106-98-9 1-butylene 
• 65878-53-7 (+)-(1R,2S)-allocoronamic acid 
• 65878-52-6 (+)-(1S,2R)-allocoronamic acid 
• 98189-21-0 (1R,2S)-1-((S)-2-Ethoxycarbonyloxy-2-phenyl-acetylamino)-2-ethyl-cyclopropanecarboxylic acid methyl ester 
• 98244-44-1 (1S,2R)-1-((R)-2-Ethoxycarbonyloxy-2-phenyl-acetylamino)-2-ethyl-cyclopropanecarboxylic acid methyl ester 
• 98244-40-7 (1S,2R)-1-((S)-2-Ethoxycarbonyloxy-2-phenyl-acetylamino)-2-ethyl-cyclopropanecarboxylic acid methyl ester 

Relevant articles and documents

ASYMMETRIC SYNTHESIS OF CIS AND TRANS 2-METHYL AND 2-ETHYL 1-AMINO CYCLOPROPANECARBOXYLIC ACIDS

A new four step asymmetric synthesis of 2-methyl and 2-ethyl 1-amino cyclopropane carboxylic acids resulted from the cycloaddition of diazomethane to the corresponding chirally derivatized dehydro-aminoacid.

Titanium-mediated diastereoselective formation of (E)- or (Z)-2-substituted 1-vinylcyclopropanols: Scope and limitation, applications

Titanium-mediated cyclopropanation of α,β-unsaturated esters failed to provide 1-vinylcyclopropanol derivatives in useful yields, but (E)-2-substituted-1-vinylcyclopropanols were formed diastereoselectively from O-protected β-oxo- and β-halo esters, with the allylic double bond being created subsequently (Knoevenagel condensation or dehydrohalogenation). Titanium-mediated cyclopropanation of homoallyl alk-2-enoates, on the other hand, directly provided the corresponding Z diastereomers. Palladium(0)-catalysed azidation of their sulfonic esters (tosylate, mesylate), azide reduction, and subsequent double bond cleavage afforded (E)- or (Z)-2-alkyl-2,3-methanoamino acids, although improvements are required to perform the total asymmetric syntheses of molecules with three membered-rings by these methods. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.

Utilization of [2 + 1] cycloaddition reactions of 1-seleno-2- silylethenes: A novel synthesis of 2-substituted 1-aminocyclopropane-1- carboxylic acids

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