6340-63-2

Basic information

• Product Name: methyl 2,3,4-tri-O-benzoyl-6-deoxy-6-iodohexopyranoside
• CAS NO: 6340-63-2
• Molecular Formula: C₂₈H₂₅IO₈
• Molecular Weight: 616.3978
• Mol File: 6340-63-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 674.2°C at 760 mmHg
• Flash Point: 361.6°C
• Density: 1.55g/cm³
• Vapor Pressure: 4.87E-18mmHg at 25°C
• Refractive Index: 1.636
• CAS DataBase Reference: methyl 2,3,4-tri-O-benzoyl-6-deoxy-6-iodohexopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2,3,4-tri-O-benzoyl-6-deoxy-6-iodohexopyranoside(6340-63-2)
• EPA Substance Registry System: methyl 2,3,4-tri-O-benzoyl-6-deoxy-6-iodohexopyranoside(6340-63-2)

Safety Data

• Hazardous Substances Data: 6340-63-2(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 198338-59-9 methyl 2,3,4-tri-O-benzoyl-6-O-trityl-α-D-mannopyranoside 
• 34234-44-1 methyl 2,3,4-tri-O-benzoyl-α-D-mannopyranoside 
• 617-04-9 (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol 
• 52290-43-4 methyl 6-deoxy-6-iodo-α-D-mannopyrannoside 
• 98-88-4 benzoyl chloride 
• 92516-60-4 methyl 2,3,4-tri-O-benzoyl-6-O-p-toluenesulfonyl-α-D-mannopyranoside 

Downstream Products

• 18929-79-8 methyl 2,3,4-tri-O-benzoyl-6-bromo-6-deoxy-α-D-mannopyranoside 
• 81823-33-8 methyl (methyl 2,3,4-tri-O-benzoyl-6-deoxy-α-D-manno-heptopyranosid)uronate 
• 95664-66-7 methyl 2,3,4-tri-O-benzoyl-6-deoxy-α-D-lyxo-hex-5-enopyranoside 
• 7512-03-0 methyl 2,3,4-tri-O-benzoyl-6-deoxy-α-D-mannopyranoside 
• 109681-61-0 methyl 2,3,4-tri-O-benzoyl-6-deoxy-β-L-gulopyranoside 
• 1017245-55-4 ethyl 2,3,4-tri-O-benzoyl-6-deoxy-1-thio-α-D-mannopyranoside 

Relevant articles and documents

Studies on the substrate specificity of a GDP-mannose pyrophosphorylase from Salmonella enterica

A series of methoxy and deoxy derivatives of mannopyranose-1-phosphate (Manp-1P) were chemically synthesized, and their ability to be converted into the corresponding guanosine diphosphate mannopyranose (GDP-Manp) analogues by a pyrophosphorylase (GDP-ManPP) from Salmonella enterica was studied. Evaluation of methoxy analogues demonstrated that GDP-ManPP is intolerant of bulky substituents at the C-2, C-3, and C-4 positions, in turn suggesting that these positions are buried inside the enzyme active site. Additionally, both the 6-methoxy and 6-deoxy Manp-1P derivatives are good or moderate substrates for GDP-ManPP, thus indicating that the C-6 hydroxy group of the Manp-1P substrate is not required for binding to the enzyme. When taken into consideration with other previously published work, it appears that this enzyme has potential utility for the chemoenzymatic synthesis of GDP-Manp analogues, which are useful probes for studying enzymes that employ this sugar nucleotide as a substrate.