63401-12-7 Usage
Description
1-(2-piperidyl)propan-1-ol, with the molecular formula C8H17NO, is a primary alcohol featuring a piperidine ring connected to a propane chain. This chemical compound is recognized for its unique structure and properties, which contribute to its potential in various applications across different industries.
Uses
Used in Organic Synthesis:
1-(2-piperidyl)propan-1-ol is utilized as a key component in organic synthesis, serving as a building block for creating more complex molecules. Its presence in this application is attributed to its structural versatility and reactivity, allowing for the formation of a wide range of compounds.
Used in Pharmaceutical Manufacturing:
In the pharmaceutical industry, 1-(2-piperidyl)propan-1-ol is employed as a crucial intermediate in the production of various drugs. Its unique structure enables it to be a valuable asset in the development of new medications, particularly those targeting the central nervous system.
Used in Agrochemical Production:
1-(2-piperidyl)propan-1-ol also finds application in the agrochemical sector, where it is used as a starting material for the synthesis of different agrochemicals. Its role in this industry is due to its ability to be modified and incorporated into molecules with specific pesticidal or herbicidal properties.
Safety Considerations:
Given its classification as a flammable liquid and potential irritant to the skin and eyes, it is essential to handle 1-(2-piperidyl)propan-1-ol with care and adhere to proper safety protocols to minimize risks and ensure a safe working environment.
Check Digit Verification of cas no
The CAS Registry Mumber 63401-12-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,4,0 and 1 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 63401-12:
(7*6)+(6*3)+(5*4)+(4*0)+(3*1)+(2*1)+(1*2)=87
87 % 10 = 7
So 63401-12-7 is a valid CAS Registry Number.
63401-12-7Relevant articles and documents
Stereoselective synthesis of (-)-α-conhydrine and its pyrrolidine analogue
Dong, Guang Ri,Hong, Seungmin,Kim, Seung In,Kim, In Su,Jung, Young Hoon
, p. 4200 - 4205 (2012/10/07)
The stereoselective synthesis of (-)-α-conhydrine and its pyrrolidine analogue was achieved from readily available D-erythronolactone. The key step of this synthesis includes a highly regioselective and diastereoselective addition of chlorosulfonyl isocyanate to 1,2-anti-dibenzyl ether to afford the 1,2-anti-amino alcohol. The total synthesis of (-)-α-conhydrine and its pyrrolidine analogue starting from readily available D-erythronolactone was achieved via the regioselective and diastereoselective allylic amination of anti-1,2-dibenzyl ether by using chlorosulfonyl isocyanate.
Highly enantioselective synthesis of chiral cyclic amino alcohols and conhydrine by ruthenium-catalyzed asymmetric hydrogenation
Liu, Sheng,Xie, Jian-Hua,Li, Wei,Kong, Wei-Ling,Wang, Li-Xin,Zhou, Qi-Lin
supporting information; experimental part, p. 4994 - 4997 (2009/12/28)
A highly efficient enantio- and diastereoselective synthesis of chiral cis-β-N-alkyl/arylamino cyclic alcohols has been realized by asymmetric hydrogenation of racemic α-amino cyclic ketones via DKR catalyzed by [RuCl2((S)-Xyl-SDP)((R,R)-DPEN)]. The enantioselectivities of the reaction were up to 99.9% ee with 99:1 cis-selectivities. A practical catalytic asymmetric synthesis of all four isomers of conhydrine was also developed.
Asymmetric synthesis of (-)-α-conhydrine
Kandula, Subba Rao V.,Kumar, Pradeep
, p. 3268 - 3274 (2007/10/03)
The enantioselective synthesis of (-)-α-conhydrine has been achieved by two different synthetic routes. The key steps include Sharpless asymmetric dihydroxylation, regioselective opening of a cyclic sulfate and Wittig olefination.
