6341-56-6

Basic information

• Product Name: 1-Naphthaleneaceticacid, a-methylene-
• Synonyms: NSC46721
• CAS NO: 6341-56-6
• Molecular Formula: C₁₃H₁₀O₂
• Molecular Weight: 198.2173
• Mol File: 6341-56-6.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 378.8°Cat760mmHg
• Flash Point: 278°C
• Density: 1.208g/cm³
• CAS DataBase Reference: 1-Naphthaleneaceticacid, a-methylene-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Naphthaleneaceticacid, a-methylene-(6341-56-6)
• EPA Substance Registry System: 1-Naphthaleneaceticacid, a-methylene-(6341-56-6)

Safety Data

• Hazardous Substances Data: 6341-56-6(Hazardous Substances Data)

Usage

Synonym

NAA

Class

Organic compounds

Subclass

Naphthalenes

Type

Synthetic auxin or plant hormone

Uses

Promotes root formation and growth in plant cuttings, stimulates root development in young plants, increases fruit set in vegetables, controls the growth of weeds, and in the production of plant growth regulators and herbicides

Toxicity

Moderately toxic to humans and should be handled with care.

Upstream product

• 335208-46-3 2-naphthalen-1-yl-acrylic acid methyl ester 
• 54160-60-0 ethyl 2-(naphthalen-1-yl)acrylate 
• 86-87-3 naphth-1-yl acetic acid 
• 124-38-9 carbon dioxide 
• 15727-65-8 1-ethynylnaphthalene 
• 703-55-9 1-naphthylmagnesiumbromide 
• 33656-65-4 ethyl 2-(1-naphthyl)-2-oxoacetate 
• 90-11-9 1-Bromonaphthalene 
• 110-89-4 piperidine 
• 66-77-3 1-naphthaldehyde 
• 415973-98-7 diethoxyphosphoryl-2-(naphth-1-yl)-acetic acid methyl ester 
• 109230-87-7 1-bromo-naphth-1-yl-acetic acid methyl ester 
• 2876-78-0 methyl 1-naphthylacetate 

Downstream Products

• 1346947-88-3 C₂₂H₁₉NO₃S 
• 1189371-39-8 N-benzyl-2-(naphthalen-1-yl)acrylamide 

Relevant articles and documents

Palladium-catalyzed cascade synthesis of spirocyclic oxindoles via regioselective C2-H arylation and C8-H alkylation of naphthalene ring

A simultaneous C2-H arylation and C8-H alkylation of naphthalene ring has been achieved by palladium-catalyzed cascade reaction of N-(2-halophenyl)-2-(naphthalen-1-yl)acrylamides with aryl iodides, which provides an efficient method for synthesizing various aryl-substituted spirocyclic oxindoles. The protocol enables three C–C bonds formation via an intramolecular Heck reaction and sequentially regioselective C–H bond activation.

Palladium-Catalyzed Asymmetric Hydroesterification of α-Aryl Acrylic Acids to Chiral Substituted Succinates

A palladium-catalyzed asymmetric hydroesterification of α-aryl acrylic acids with CO and alcohol was developed, preparing a variety of chiral α-substituted succinates in moderate yields with high ee values. The kinetic profile of the reaction progress revealed that the alkene substrate first underwent the hydroesterification followed by esterification with alcohol. The origin of the enantioselectivity was elucidated by density functional theory computation.

Cobalt-Catalyzed Vinylic C-H Addition to Formaldehyde: Synthesis of Butenolides from Acrylic Acids and HCHO

A carboxyl-assisted C-H functionalization of acrylic acids with formaldehyde to give butenolides is described. It is the first time that the addition of an inert vinylic C-H bond to formaldehyde has been achieved via cobalt-catalyzed C-H activation. The unique reactivity of the cobalt species was observed when compared with related Rh or Ir catalysts. γ-Hydroxymethylated butenolides were produced by the treatment of Na2CO3 after the catalytic reaction in one pot.