63449-79-6

Basic information

• Product Name: 2-Butanone, 4-(2-methoxyphenyl)-
• CAS NO: 63449-79-6
• Molecular Formula: C11H14O2
• Molecular Weight: 178.231
• Mol File: 63449-79-6.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: 2-Butanone, 4-(2-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butanone, 4-(2-methoxyphenyl)-(63449-79-6)
• EPA Substance Registry System: 2-Butanone, 4-(2-methoxyphenyl)-(63449-79-6)

Safety Data

• Hazardous Substances Data: 63449-79-6(Hazardous Substances Data)

Upstream product

• 598-32-3 2-hydroxy-3-butene 
• 529-28-2 4-iodoanisol 
• 90-04-0 2-methoxy-phenylamine 
• 78-94-4 methyl vinyl ketone 
• 61844-27-7 2-methylchroman-2-ol 
• 74-88-4 methyl iodide 
• 116585-12-7 2-((tert-butyldimethylsilyl)oxy)benzaldehyde 
• 96013-79-5 {2-[(tert-butyldimethylsilyl)oxy]phenyl}methanol 
• 10542-87-7 (E)-4-(2-methoxyphenyl)but-3-en-2-one 
• 135-02-4 ortho-anisaldehyde 
• 60438-50-8 2-methoxybenzalacetone 
• 578-57-4 2-bromoanisole 
• 590-90-9 1-Hydroxy-3-butanone 
• 100-66-3 methoxybenzene 

Downstream Products

• 199107-07-8 5-(2-methoxy-phenyl)-3-oxo-valeric acid ethyl ester 
• 1678-93-9 butylcyclohexane 
• 10528-67-3 4-cyclohexyl-2-butanol 
• 871884-00-3 4-(2-methoxy-cyclohexyl)-butan-2-ol 
• 18272-65-6 4-(2-hydroxyphenyl)-2-methyl-1-butene 
• 18272-85-0 4-(2-methoxyphenyl)-2-methyl-1-butene 
• 72734-73-7 1,1-dimethyl-3-(2-methoxy-phenyl)-propanamine 
• 56052-48-3 4-(2-methoxyphenyl)-2-methylbutan-2-ol 
• 1200399-07-0 4-methyl-5-{[2-(methyloxy)phenyl]methyl}-1,3-thiazol-2-amine hydrochloride 
• 1200435-57-9 C₁₂H₁₄N₂OS 
• 1175532-66-7 3-bromo-4-[2-(methyloxy)phenyl]-2-butanone 
• 70959-78-3 5-{1-Hydroxy-2-[3-(2-methoxy-phenyl)-1-methyl-propylamino]-ethyl}-2-methoxy-benzenesulfonamide; hydrochloride 
• 85276-19-3 2-Hydroxy-5-{1-hydroxy-2-[3-(2-methoxy-phenyl)-1-methyl-propylamino]-ethyl}-benzenesulfonamide; hydrochloride 
• 70959-02-3 5-{1-Hydroxy-2-[3-(2-methoxyphenyl)-1-methylpropylamino]-ethyl}-2-methylbenzenesulfonamide hydrochloride 

Relevant articles and documents

8-Hydroxyquinolin-2(1H)-one analogues as potential β2-agonists: Design, synthesis and activity study

β2-Agonists that bind to plasmalemmal β2-adrenoceptors causing cAMP accumulation are widely used as bronchodilators in chronic respiratory diseases. Here, we designed and synthesized a group of 8-hydroxyquinolin-2(1H)-one analogues and studied their β2-agonistic activities with a cellular cAMP assay. Compounds B05 and C08 were identified as potent (EC50 2-agonists among the compounds tested. They behaved as partial β2-agonists in non-overexpressed HEK293 cells, and possessed rapid smooth muscle relaxant actions and long duration of action in isolated guinea pig tracheal strip preparations. In summary, B05 and C08 are β2-agonists with potential applicability in chronic respiratory diseases.

Dopamine D2 receptor selective agonist and application thereof

The invention relates to a dopamine D2 receptor selective agonist and application thereof. Specifically, the invention discloses an agonist with selectivity to DRD2 and discloses a potential application value of the agonist in disease treatment. The invention discloses an agonist with DRD2 selectivity for the first time, and the specific targeting DRD2 of the agonist can play a role in treating low dopamine related diseases such as Parkinson's disease, attention deficit hyperactivity disorder, pituitary adenoma, hyperprolactinemia, hyperactivity leg syndrome, negative schizophrenia and the like while side effects are reduced to the maximum extent.

A Lewis Base Catalysis Approach for the Photoredox Activation of Boronic Acids and Esters

We report herein the use of a dual catalytic system comprising a Lewis base catalyst such as quinuclidin-3-ol or 4-dimethylaminopyridine and a photoredox catalyst to generate carbon radicals from either boronic acids or esters. This system enabled a wide range of alkyl boronic esters and aryl or alkyl boronic acids to react with electron-deficient olefins via radical addition to efficiently form C?C coupled products in a redox-neutral fashion. The Lewis base catalyst was shown to form a redox-active complex with either the boronic esters or the trimeric form of the boronic acids (boroxines) in solution.