634598-39-3

Basic information

• Product Name: Cyclooctanone, 2-(phenylmethoxy)-
• CAS NO: 634598-39-3
• Molecular Formula: C15H20O2
• Molecular Weight: 232.323
• Mol File: 634598-39-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Cyclooctanone, 2-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclooctanone, 2-(phenylmethoxy)-(634598-39-3)
• EPA Substance Registry System: Cyclooctanone, 2-(phenylmethoxy)-(634598-39-3)

Safety Data

• Hazardous Substances Data: 634598-39-3(Hazardous Substances Data)

Upstream product

• 56879-17-5 (5Z)-2-hydroxycycloocten-1-one 
• 496-82-2 2-hydroxycylooctanone 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 

Downstream Products

• 85866-03-1 cyclooctane-1,2,3-triol 
• 85866-03-1 (1S,2R)-Cyclooctane-1,2,3-triol 
• 664987-30-8 3-benzyloxy-1,2-cyclooctanedione 
• 664987-32-0 cis-2,3-dihydroxycyclooctanone 
• 85866-03-1 cyclooctane-1,2,3-triol 
• 664987-26-2 trans-2,8-dihydroxycyclooctanone 
• 500573-04-6 2-benzyl-2-hydroxy-cyclooctanone 

Relevant articles and documents

Synthesis of Stereoisomeric Medium-Ring α,α′-Dihydroxy Cycloalkanones

The stereochemical course of the epoxidation of the silyl enol ethers of 2-tert-butyldimethylsilyl-oxycycloheptanone and -cyclooctanone has been investigated and shown to proceed exclusively anti to the existing α-substituent. 2-(Benzyloxy)cyclooctanone b

Divergent regioselectivity in the base-promoted reactions of cyclic eight-membered α-ketols with activated halides

(Matrix presented) Deprotonation of 2-hydroxycyclooctanone followed by exposure to an allylic or benzylic halide proceeds very selectively to give the product of C-alkylation. The effect of Δ5,6-unsaturation is to promote instead the formation of the O-alkylated derivative. This crossover in kinetic preference is attributed to an inability of the olefinic system to attain a conformation conducive to proton abstraction at C-2.