634905-12-7

Basic information

• Product Name: 4-(4-BROMOPHENYL)MORPHOLIN-3-ONE
• Synonyms: 4-(4-BROMOPHENYL)MORPHOLIN-3-ONE;4-(4-Bromophenyl)-3-morpholinone
• CAS NO: 634905-12-7
• Molecular Formula: C₁₀H₁₀BrNO₂
• Molecular Weight: 256.1
• Mol File: 634905-12-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(4-BROMOPHENYL)MORPHOLIN-3-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-BROMOPHENYL)MORPHOLIN-3-ONE(634905-12-7)
• EPA Substance Registry System: 4-(4-BROMOPHENYL)MORPHOLIN-3-ONE(634905-12-7)

Safety Data

• Hazardous Substances Data: 634905-12-7(Hazardous Substances Data)

Usage

General Description

4-(4-Bromophenyl)morpholin-3-one is a chemical compound that belongs to the class of morpholine derivatives. It is a white to off-white solid that is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 4-(4-BROMOPHENYL)MORPHOLIN-3-ONE is known for its potential applications in the field of medicinal chemistry, particularly in the development of drugs targeting various diseases and disorders. It has also been utilized in research and development studies to investigate its pharmacological properties and biological activities. Additionally, 4-(4-Bromophenyl)morpholin-3-one has been studied for its potential as a reactive building block in organic synthesis and for its use as a reagent in chemical reactions for the preparation of other valuable compounds. Overall, this chemical compound has a wide range of potential applications and is a valuable tool in various scientific and industrial endeavors.

Upstream product

• 109-11-5 morpholine-3-one 
• 589-87-7 1,4-bromoiodobenzene 
• 29518-11-4 4-phenylmorpholin-3-one 
• 92-53-5 4-Phenylmorpholine 
• 106-37-6 1.4-dibromobenzene 
• 30483-75-1 4-bromophenyl-morpholine 

Downstream Products

• 928631-04-3 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)morpholin-3-one 
• 1400688-48-3 4-(((1R,3S)-3-amino-2,2,3-trimethylcyclopentyl)amino)-6-(4-(3-oxo-4-morpholinyl)phenyl)pyrrolo[1,2-b]pyridazine-3-carboxamide 
• 634903-97-2 N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-[4-(3-oxo-4-morpholinyl)phenyl]-1-benzofuran-2-carboxamide hydrochloride 
• 634903-76-7 N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-[4-(3-oxo-4-morpholinyl)phenyl]-1-benzothiophene-2-carboxamide hydrochloride 
• 446292-08-6 2-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-1H-isoindole-1,3(2H)-dione 

Relevant articles and documents

Activated charcoal supported copper nanoparticles: A readily available and inexpensive heterogeneous catalyst for the N-arylation of primary amides and lactams with aryl iodides

A novel heterogeneous copper catalyst has been developed by supporting copper nanoparticles on activated charcoal via in situ reducing copper(II) with aqueous hydrazine as reductant. The characterization of Cu/C catalyst showed that the Cu0 nano-particles were formed on the surface of charcoal. This catalyst displayed good catalytic activities toward the N-arylation of primary amides and lactams with aryl iodides.

CATHEPSIN K INHIBITOR AND APPLICATION THEREOF

The invention relates to capthepsin K inhibitors and uses thereof, specifically relates to a class of compounds having the formula (I) which are used for treating or preventing cathepsin dependent diseases or conditions, specifically, wherein the cathepsin is capthepsin K. The compounds and compositions thereof can be used as bone resorption inhibitors for the treatment of associated diseases.

PYRROLOPYRIDAZINE JAK3 INHIBITORS AND THEIR USE FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES

Disclosed are compounds of formula (I) and pharmaceutically acceptable salts thereof. The compounds of formula (I) inhibit tyrosine kinase activity of JAK3, thereby making them useful for the treatment of inflammatory and autoimmune diseases.