635-86-9

Basic information

• Product Name: gamma-glutamyl-2-naphthylamide
• Synonyms: gamma-glutamyl-2-naphthylamide;(4S)-4-amino-5-(naphthalen-2-ylamino)-5-oxopentanoic acid;(4S)-4-amino-5-keto-5-(2-naphthylamino)valeric acid;(4S)-4-azanyl-5-(naphthalen-2-ylamino)-5-oxo-pentanoic acid;H-Glu-βNA;H-Glu-bNA;N-(alpha-L-glutamyl)-2-naphthylamine;(S)-4-AMINO-5-(NAPHTHALEN-2-YLAMINO)-5-OXOPENTANOIC ACID
• CAS NO: 635-86-9
• Molecular Formula: C15H16N2O3
• Molecular Weight: 272.3
• Mol File: 635-86-9.mol
• Article Data: 0

Chemical Properties

• Melting Point: 174-175 °C
• Boiling Point: 590.7°C at 760 mmHg
• Flash Point: 311.1°C
• Appearance: /
• Density: 1.329g/cm³
• Vapor Pressure: 8.42E-15mmHg at 25°C
• Refractive Index: 1.679
• PKA: 4.24±0.10(Predicted)
• CAS DataBase Reference: gamma-glutamyl-2-naphthylamide(CAS DataBase Reference)
• NIST Chemistry Reference: gamma-glutamyl-2-naphthylamide(635-86-9)
• EPA Substance Registry System: gamma-glutamyl-2-naphthylamide(635-86-9)

Safety Data

• Hazardous Substances Data: 635-86-9(Hazardous Substances Data)

Usage

Description

Gamma-glutamyl-2-naphthylamide, also known as H-Glu-βNA, is an L-glutamic acid derivative that is formed by the formal condensation of the alpha-carboxy group of L-glutamic acid with the amino group of 2-naphthylamine. It is a compound widely utilized in various applications due to its unique properties.

Uses

Used in Diagnostic Applications:
Gamma-glutamyl-2-naphthylamide is used as a substrate for the fluorimetric determination of aminopeptidases in the human brain. This application is significant because it aids in the study and understanding of aminopeptidase activity, which is crucial for various biological processes and can be indicative of certain neurological conditions.
Used in Pharmaceutical Research:
In the pharmaceutical industry, gamma-glutamyl-2-naphthylamide serves as a valuable compound for research purposes. Its unique structure allows scientists to study its interactions with various biological molecules, potentially leading to the development of new drugs and therapies.
Used in Analytical Chemistry:
Gamma-glutamyl-2-naphthylamide can be employed as a reagent in analytical chemistry for the detection and quantification of specific enzymes or other biomolecules. Its fluorescent properties make it an ideal candidate for assays and other laboratory tests.

InChI:InChI=1/C15H16N2O3/c16-13(7-8-14(18)19)15(20)17-12-6-5-10-3-1-2-4-11(10)9-12/h1-6,9,13H,7-8,16H2,(H,17,20)(H,18,19)/t13-/m0/s1

Upstream product

• 4124-76-9 N-(benzyloxycarbonyl)-L-glutamic acid anhydride 
• 91-59-8 naphthalen-2-ylamine 
• 112982-92-0 (Z)-LLE-bNA