63500-71-0 Usage
Description
2-Isobutyl-4-hydroxy-4-methyltetrahydro-2H-pyran is a colorless to pale yellow liquid with a fresh, soft, and natural floral odor. It is synthesized through the cyclocondensation of 3-methyl-3-buten-1-ol with 3-methylbutanal on silica gel and alumina in the absence of solvents, resulting in a mixture of cis/trans-isomers. The proportion of the more valuable cis-isomer can be increased by using dilute sulfuric acid as a catalyst.
Uses
Used in Fragrance Industry:
2-Isobutyl-4-hydroxy-4-methyltetrahydro-2H-pyran is used as a fragrance ingredient for its fresh, soft, and natural floral odor. It adds a pleasant and distinct scent to various perfumes, colognes, and other fragrance products.
Used in Flavor Industry:
In the flavor industry, 2-Isobutyl-4-hydroxy-4-methyltetrahydro-2H-pyran is used as an additive to enhance the taste and aroma of food and beverages. Its natural floral scent can provide a unique and appealing flavor profile to a wide range of products.
Used in Cosmetics and Personal Care Industry:
2-Isobutyl-4-hydroxy-4-methyltetrahydro-2H-pyran is used as a key ingredient in cosmetics and personal care products due to its pleasant scent and ability to improve the overall sensory experience of these products. It can be found in various formulations such as lotions, creams, shampoos, and other personal care items.
Used in the Pharmaceutical Industry:
In the pharmaceutical industry, 2-Isobutyl-4-hydroxy-4-methyltetrahydro-2H-pyran may be utilized for its potential therapeutic properties or as a component in the development of new drugs. Its chemical structure and properties make it a candidate for further research and application in the medical field.
Flammability and Explosibility
Nonflammable
Trade name
Florol? (Firmenich), Florosa (Givaudan), Florosol (Innospec),
Pyranol (BASF).
Check Digit Verification of cas no
The CAS Registry Mumber 63500-71-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,5,0 and 0 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 63500-71:
(7*6)+(6*3)+(5*5)+(4*0)+(3*0)+(2*7)+(1*1)=100
100 % 10 = 0
So 63500-71-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H20O2/c1-8(2)6-9-7-10(3,11)4-5-12-9/h8-9,11H,4-7H2,1-3H3
63500-71-0Relevant articles and documents
PRODUCTION OF 2-SUBSTITUTED 4-HYDROXY-4-METHYL-TETRAHYDROPYRANS FROM STARTING MATERIALS CONTAINING 2-ALKYL-4,4-DIMETHYL-1,3-DIOXANES
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Paragraph 0266, (2017/06/15)
The present invention relates to a method for preparing 2-substituted 4-hydroxy-4-methyltetrahydropyrans from starting materials comprising at least one 2-alkyl-4,4-dimethyl-1,3-dioxane.
Contribution to elucidation of the mechanism of preparation of 2-isobutyl-4-methyltetrahydro-2H-pyran-4-ol
Vyskoilov, Elika,Rezkov, Lucie,Vrbkov, Eva,Paterov, Iva,erven, Libor
, p. 725 - 733 (2016/04/26)
The effects of catalyst type (sulfuric acid, Amberlyst 15, p-toluenesulfonic acid, and p-dodecylbenzenesulfonic acid) and of addition of water on the preparation of 2-isobutyl-4-methyltetrahydro-2H-pyran-4-ol by Prins cyclization were studied. It was discovered that in the absence of added water the amphiphilic character of the acid had the main effect and that organic acids were unsuitable for preparation of this compound. From the perspective of the ratio of the amount of the desired product to that of dihydropyrans, after addition of water the results obtained by use of p-toluenesulfonic acid (ratio 3.5, selectivity 67 %) were comparable with those obtained by use of sulfuric acid and were better than those obtained by use of Amberlyst 15 (ratio 2.3, selectivity 68 %). A detailed study of the mechanism confirmed that addition of water to the double bonds of dihydropyrans does not occur.
ISOMERISATION OF 2-R-4,4-DIMETHYL- AND 2-R-4-METHYL-4-PHENYL-1,3-DIOXANES TO 2-R-4-METHYL- AND 2-R-4-PHENYLTETRAHYDROPYRAN-4-OLS
Romanov, N. A.,Kantor, E.A.,Brudnik, I. M.,Musavirov, R. S.,Kiladze, T. K.,Rakhmankulov, D. L.
, p. 2526 - 2528 (2007/10/02)
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