635304-44-8

Basic information

• Product Name: (1R, 2S)-1-[4-(benzyloxy)phenyl]-2-[((1R)-phenylethyl)amino]-1-propanol
• Synonyms: (1R, 2S)-1-[4-(benzyloxy)phenyl]-2-[((1R)-phenylethyl)amino]-1-propanol
• CAS NO: 635304-44-8
• Molecular Weight: 361.484
• Mol File: 635304-44-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R, 2S)-1-[4-(benzyloxy)phenyl]-2-[((1R)-phenylethyl)amino]-1-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R, 2S)-1-[4-(benzyloxy)phenyl]-2-[((1R)-phenylethyl)amino]-1-propanol(635304-44-8)
• EPA Substance Registry System: (1R, 2S)-1-[4-(benzyloxy)phenyl]-2-[((1R)-phenylethyl)amino]-1-propanol(635304-44-8)

Safety Data

• Hazardous Substances Data: 635304-44-8(Hazardous Substances Data)

Upstream product

• 635304-39-1 (2S)-1-[4-(benzyloxy)phenyl]-2-[((1R)-phenylethyl)amino]-1-propanone methanesulfonate 

Downstream Products

• 552-85-2 4-((1R,2S)-2-amino-1-hydroxypropyl)phenol 

Relevant articles and documents

PROCESS FOR PRODUCING OPTICALLY ACTIVE s-AMINO ALCOHOL

A process for easily producing an optically active β-amino alcohol useful as a pharmaceutical intermediate from an inexpensive, readily available starting material is provided. A readily available α-substituted ketone is reacted with an optically active amine to yield a diastereomer mixture of an optically active α-substituted aminoketone. One of the diastereomers is isolated optionally after the diastereomers are converted to salts with an acid. The optically active α-substituted aminoketone or a salt thereof thus isolated was stereoselectively reduced to yield an optically active β-substituted amino alcohol. The optically active β-substituted amino alcohol is subjected to hydrogenolysis to produce an optically active β-amino alcohol or a salt thereof.