635310-17-7

Basic information

• Product Name: methyl 4-(2-{(5R)-2-oxo-5-[(1E)-3-oxohept-1-enyl]pyrrolidin-1-yl}ethyl)benzoate
• Synonyms: methyl 4-(2-{(5R)-2-oxo-5-[(1E)-3-oxohept-1-enyl]pyrrolidin-1-yl}ethyl)benzoate
• CAS NO: 635310-17-7
• Molecular Weight: 357.45
• Mol File: 635310-17-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 4-(2-{(5R)-2-oxo-5-[(1E)-3-oxohept-1-enyl]pyrrolidin-1-yl}ethyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(2-{(5R)-2-oxo-5-[(1E)-3-oxohept-1-enyl]pyrrolidin-1-yl}ethyl)benzoate(635310-17-7)
• EPA Substance Registry System: methyl 4-(2-{(5R)-2-oxo-5-[(1E)-3-oxohept-1-enyl]pyrrolidin-1-yl}ethyl)benzoate(635310-17-7)

Safety Data

• Hazardous Substances Data: 635310-17-7(Hazardous Substances Data)

Upstream product

• 61728-15-2 2-oxohexylphosphonic acid dimethyl ester 
• 635309-85-2 (R)-methyl 4-(2-(2-formyl-5-oxopyrrolidin-1-yl)ethyl) benzoate 

Downstream Products

• 635310-18-8 methyl 4-(2-{(2R)-2-[(1E,3S)-3-hydroxyhept-1-enyl]-5-oxopyrrolidin-1-yl}ethyl)benzoate 

Relevant articles and documents

Synthesis and evaluation of a γ-lactam as a highly selective EP2 and EP4 receptor agonist

γ-Lactam analogs (2) of EP4 receptor agonists were identified by substitution of the pyrazolidinone ring (1) with a pyrrolidinone ring. Several compounds (such as 2a, 2h) with high potency, selectivity and acceptable PK profiles were discovered. These were assessed in animal models of ovulation induction and bronchoconstriction.