63589-93-5

Basic information

• Product Name: valyl-leucyl-lysine 4-nitroanilide
• Synonyms: valyl-leucyl-lysine 4-nitroanilide
• CAS NO: 63589-93-5
• Molecular Formula: C₂₃H₃₈N₆O₅
• Molecular Weight: 478.58
• Mol File: 63589-93-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 778.3°C at 760 mmHg
• Flash Point: 424.5°C
• Appearance: /
• Density: 1.187g/cm³
• Vapor Pressure: 3.65E-24mmHg at 25°C
• Refractive Index: 1.561
• PKA: 12.43±0.70(Predicted)
• CAS DataBase Reference: valyl-leucyl-lysine 4-nitroanilide(CAS DataBase Reference)
• NIST Chemistry Reference: valyl-leucyl-lysine 4-nitroanilide(63589-93-5)
• EPA Substance Registry System: valyl-leucyl-lysine 4-nitroanilide(63589-93-5)

Safety Data

• Hazardous Substances Data: 63589-93-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C23H38N6O5/c1-5-15(4)20(28-22(31)19(25)14(2)3)23(32)27-18(8-6-7-13-24)21(30)26-16-9-11-17(12-10-16)29(33)34/h9-12,14-15,18-20H,5-8,13,24-25H2,1-4H3,(H,26,30)(H,27,32)(H,28,31)/t15?,18-,19+,20?/m0/s1

Downstream Products

• 100-01-6 4-nitro-aniline 

Relevant articles and documents

Hybrid plasminogen activators with improved thrombolytic properties and drugs comprising these plasminogen activators

The invention relates to plasminogen activators ob-tained by expression of fused cDNA encoding fragments of human tissue-type plasminogen activator (t-PA) and of human urokinase-type plasminogen activator (u-PA), by combining the fibrin-affinity of t-PA with the fibrin-specificity of u-PA in the single chain form (scu-PA) and/or with the enzymatic activity of u-PA having the two-chain form (tcu-PA). It is preferably a hybrid molecule obtained by fusion of at least a region part of the NH2-terminal region of t-PA to at least a part region of the COOH-terminal region of scu-PA, most preferably the NH2-terminal amino acids 1 to 263 of t-PA, fused to the COOH-terminal amino acids 144 to 411 of scu-PA. The invention relates further to a recombinant DNA molecule which yields said hybrid plasminogen activators; the respective mammalian expression vector containing said DNA sequence; a transfected mammalian cell line which com-prises said recombinant DNA molecule; and to the method for the preparation of plasminogen activators.