63591-89-9

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2-[(4-chlorobenzoyl)oxy]-
• CAS NO: 63591-89-9
• Molecular Formula: C15H8ClNO4
• Molecular Weight: 301.686
• Mol File: 63591-89-9.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2-[(4-chlorobenzoyl)oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-[(4-chlorobenzoyl)oxy]-(63591-89-9)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-[(4-chlorobenzoyl)oxy]-(63591-89-9)

Safety Data

• Hazardous Substances Data: 63591-89-9(Hazardous Substances Data)

Upstream product

• 122-01-0 4-chloro-benzoyl chloride 
• 524-38-9 N-hydroxyphthalimide 
• 106-43-4 para-chlorotoluene 
• 104-88-1 4-chlorobenzaldehyde 
• 873-76-7 para-Chlorobenzyl alcohol 
• 2203-13-6 tert-butyl p-chloroperoxybenzoate 
• 74-11-3 para-chlorobenzoic acid 

Downstream Products

• 7335-27-5 ethyl 4-chlorobenzoate 
• 15024-10-9 4-methylphenyl 4-chlorobenzoate 
• 71320-77-9 moclobemide 
• 195062-61-4 4-chlorophenylboronic acid pinacol ester 
• 39887-24-6 N-(2-phenylethyl)-p-chlorobenzamide 
• 7461-34-9 N-benzyl-p-chlorobenzamide 
• 7461-32-7 4-chloro-N-n-propylbenzamide 

Relevant articles and documents

Visible Light-Driven Efficient Synthesis of Amides from Alcohols using Cu?N?TiO2 Heterogeneous Photocatalyst

Amides were synthesized from alcohols and amines in high yields using an in situ generated active ester of N-hydroxyimide with our developed Cu?N?TiO2 catalyst at room temperature using oxygen as a sole oxidant under visible light. The catalyst can be easily prepared, robust, and recycled four times without a considerable change in catalytic activity. This developed protocol applies to a wide substrate scope and has good functional group tolerance. The application of this amidation reaction has been successfully demonstrated for the synthesis of moclobemide, an antidepressant drug, and an analog of the itopride drug on a gram scale.

N-Doped Yellow TiO2 Hollow Sphere-Mediated Visible-Light-Driven Efficient Esterification of Alcohol and N-Hydroxyimides to Active Esters

Herein we report a simple synthetic protocol for N-doped yellow TiO2 (N-TiO2) hollow spheres as an efficient visible-light-active photocatalyst using aqueous titanium peroxocarbonate complex (TPCC) solution as precursor and NH4OH. In the developed strategy, the ammonium ion of TPCC and NH4OH acts as nitrogen source and structure-directing agent. The synthesized N-TiO2 hollow spheres are capable of promoting the synthesis of active esters of N-hydroxyimide and alcohol through simultaneous selective oxidation of alcohol to aldehyde followed by cross-dehydrogenative coupling (CDC) under ambient conditions upon irradiation of visible light. It is possible to develop a novel and cost-effective one-pot strategy for the synthesis of important esters and amides on gram scale using the developed strategy. The catalytic activity of N-TiO2 hollow spheres is much superior to that of other reported N-TiO2 samples as well as TiO2 with varying morphology.

Ferric nitrate-promoted oxidative esterification of toluene with N-hydroxyphthalimide: Synthesis of N-hydroxyimide esters

A ferric nitrate-promoted cross-dehydrogenative coupling reaction of N-hydroxyphthalimide (NHPI) with toluene derivatives is reported. The reaction proceeded smoothly using molecular oxygen as an oxidant, providing an efficient method for the synthesis of