6361-33-7

Basic information

• Product Name: N-(1-Naphtyl)benzenemethaneamine
• Synonyms: Benzyl(1-naphtyl)amine;N-(1-Naphtyl)benzenemethaneamine;N-Benzyl-1-naphthalenamine;N-Benzyl-1-naphtylamine;N-Benzylnaphthalene-1-amine;N-(1-phtyl)benzenemethaneamine
• CAS NO: 6361-33-7
• Molecular Formula: C₁₇H₁₅N
• Molecular Weight: 233.3077
• Mol File: 6361-33-7.mol
• Article Data: 100

Chemical Properties

• Melting Point: 66-67 °C
• Boiling Point: 396.8 °C at 760 mmHg
• Flash Point: 208.3 °C
• Appearance: /
• Density: 1.145 g/cm³
• PKA: 4.13±0.50(Predicted)
• CAS DataBase Reference: N-(1-Naphtyl)benzenemethaneamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-Naphtyl)benzenemethaneamine(6361-33-7)
• EPA Substance Registry System: N-(1-Naphtyl)benzenemethaneamine(6361-33-7)

Safety Data

• Hazardous Substances Data: 6361-33-7(Hazardous Substances Data)

Usage

General Description

N-(1-Naphtyl)benzenemethaneamine, also known as N-(1-naphthyl)benzylamine, is a chemical compound with the molecular formula C18H17N. It is a derivative of benzene and naphthalene, and is commonly used in organic synthesis and as a chemical intermediate in the production of pharmaceuticals and dyes. It is a yellowish solid at room temperature and is soluble in organic solvents such as ethanol and diethyl ether. N-(1-Naphtyl)benzenemethaneamine is also known for its potential application as a reagent in the study and analysis of various organic compounds. Additionally, it has been found to exhibit anti-inflammatory and analgesic properties, making it of interest in the development of new therapeutic agents.

Upstream product

• 134-32-7 1-amino-naphthalene 
• 100-52-7 benzaldehyde 
• 100-44-7 benzyl chloride 
• 100-51-6 benzyl alcohol 
• 873-76-7 para-Chlorobenzyl alcohol 
• 195871-32-0 2-(2-acetylphenyl)acetaldehyde 
• 100-46-9 benzylamine 
• 83-33-0 inden-1-one 
• 767-60-2 3-Methylindene 
• 64666-42-8 1-methyl-1-indanol 
• 100-39-0 benzyl bromide 
• 108-88-3 toluene 
• 86-57-7 1-Nitronaphthalene 
• 90-15-3 α-naphthol 

Downstream Products

• 51336-07-3 N,N-dibenzyl-N-(1-naphthyl)amine 
• 157584-49-1 N-Benzyl-2,2,2-trifluoro-N-naphthalen-1-yl-thioacetamide 
• 34987-58-1 2,4-diphenylbenzo[h]quinoline 
• 1331748-56-1 N,N'-dibenzyl-(1,1'-binaphthyl)-4,4'-diamine 
• 944721-88-4 N-(but-2-ynyl)-N-benzylnaphthalen-1-amine 
• 909297-03-6 N-(2-allyl-naphthalen-1-yl)-N-benzyl-acetamide 
• 909296-99-7 (2-allyl-naphthalen-1-yl)-benzyl-amine 
• 909296-95-3 N-allyl-N-benzyl-α-naphthylamine 
• 157584-42-4 N-Benzyl-2,2,2-trifluoro-N-naphthalen-1-yl-acetamide 

Relevant articles and documents

Hydride transfer reactivity of tetrakis(trimethylphosphine)(hydrido) (nitrosyl)molybdenum(0)

The tetrakis(trimethylphosphine) molybdenum nitrosyl hydrido complex trans-Mo(PMe3)4(H)(NO) (2) and the related deuteride complex trans-Mo(PMe3)4(D)(NO) (2a) were prepared from trans-Mo(PMe3)4/s

Tungsten-Catalyzed Direct N-Alkylation of Anilines with Alcohols

The implementation of non-noble metals mediated chemistry is a major goal in homogeneous catalysis. Borrowing hydrogen/hydrogen autotransfer (BH/HA) reaction, as a straightforward and sustainable synthetic method, has attracted considerable attention in the development of non-noble metal catalysts. Herein, we report a tungsten-catalyzed N-alkylation reaction of anilines with primary alcohols via BH/HA. This phosphine-free W(phen)(CO)4 (phen=1,10-phenthroline) system was demonstrated as a practical and easily accessible in-situ catalysis for a broad range of amines and alcohols (up to 49 examples, including 16 previously undisclosed products). Notably, this tungsten system can tolerate numerous functional groups, especially the challenging substrates with sterically hindered substituents, or heteroatoms. Mechanistic insights based on experimental and computational studies are also provided.

Synthesis of an Fe-Pd bimetallic catalyst for: N -alkylation of amines with alcohols via a hydrogen auto-transfer methodology

Hydrogen auto-transfer (HAT) or borrowing hydrogen (BH) methodology which combines dehydrogenation, intermediate reaction and hydrogenation, is recognized as an excellent strategy for one-pot synthesis from an economic and environmental point of view. Although much effort has been made on the development of catalysts for HAT reactions, harsh conditions, external base or large amounts of noble metals are still required in most reported catalysis systems, and thus the exploration of a highly efficient and recyclable heterogeneous catalyst remains meaningful. In this work, a novel bimetallic catalyst, Fe10Pd1/NC500 derived from bimetallic MOF NH2-MIL-101(Fe10Pd1), has been prepared, and the catalyst exhibits superior catalytic performance for the N-alkylation of amines with alcohols via a hydrogen auto-transfer methodology. High yields of the desired products were achieved at 120 °C with an alcohol/amine molar ratio of 2?:?1 and required no external additive or solvent. A distinct enhancement in catalytic performance is observed when compared with monometallic catalysts, which can be ascribed to the "synergistic effects"inside the bimetallic alloys. The N-doped carbon support has been revealed to provide the necessary basicity which avoids the requirement of an external base. Moreover, a wide substrate range and remarkable reusability have been shown by Fe10Pd1/NC500, and this work highlights new possibilities for bimetallic catalysts applied in sustainable chemistry.