63624-28-2

Basic information

• Product Name: 2,4-DIMETHOXYBENZENESULFONYL CHLORIDE
• Synonyms: ART-CHEM-BB B019391;CHEMBRDG-BB 4006317;2,4-DIMETHOXYBENZENESULFONYL CHLORIDE;2,4-DIMETHOXYBENZENE SULPHONYL CHLORIDE;AKOS B019391;Benzenesulfonyl chloride, 2,4-dimethoxy- (9CI);2,4-dimethoxybenzenesulfonyl chloride(SALTDATA: FREE);2,4-DiMethoxyphenylsulfonyl chloride
• CAS NO: 63624-28-2
• Molecular Formula: C₈H₉ClO₄S
• Molecular Weight: 236.67
• Product Categories: SULFONYLHALIDE;Benzenesulfonyl chloride;Heterocyclic Compounds;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds
• Mol File: 63624-28-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 69-71 °C
• Boiling Point: 363.6 °C at 760 mmHg
• Flash Point: 173.7 °C
• Appearance: powder
• Density: 1.359 g/cm³
• Vapor Pressure: 3.74E-05mmHg at 25°C
• Refractive Index: 1.522
• Storage Temp.: 2-8°C
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: 2,4-DIMETHOXYBENZENESULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIMETHOXYBENZENESULFONYL CHLORIDE(63624-28-2)
• EPA Substance Registry System: 2,4-DIMETHOXYBENZENESULFONYL CHLORIDE(63624-28-2)

Safety Data

• Hazard Codes: C,Xi
• Statements: 34-43
• Safety Statements: 45-36/37/39-3-26
• RIDADR: 3261
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 63624-28-2(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C8H9ClO4S/c1-12-6-3-4-8(14(9,10)11)7(5-6)13-2/h3-5H,1-2H3

Upstream product

• 151-10-0 1,3-Dimethoxybenzene 

Downstream Products

• 492430-49-6 3-amino-5-chloro-1-[(2,4-dimethoxy-phenyl)sulphonyl]-3-(2-methoxyphenyl)-1,3-dihydro-1H-indol-2-one 
• 492431-14-8 5-Chloro-1-[(2,4-dimethoxyphenyl)sulphonyl]-3-(2-methoxyphenyl)-3-[2-oxo-2-[4-(4-pyridyl)-1-piperazinyl]ethyl]-1,3-dihydro-2H-indol-2-one 
• 492431-16-0 5-chloro-3-(2-ethoxyphenyl)-1-[(2,4-dimethoxyphenyl)sulphonyl]-3-[2-oxo-2-[4-(4-pyridyl)-1-piperazinyl]ethyl]-1,3-dihydro-2H-indol-2-one 
• 492431-20-6 3-(2-Chlorophenyl)-1-[(2,4-dimethoxyphenyl)-sulphonyl]-5-methyl-3-[2-oxo-2-[4-(2-pyridyl)-1-piperazinyl]ethyl]-1,3-dihydro-2H-indol-2-one 
• 492430-86-1 tert-butyl 2-[[5-chloro-1-[(2,4-dimethoxy-phenyl)sulphonyl]-3-(2-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]amino]acetate 
• 492430-17-8 5-chloro-1-[(2,4-dimethoxyphenyl)sulphonyl]-1H-indole-2,3-dione 
• 1452579-79-1 C₂₂H₁₈BrN₃O₇S 
• 1452579-89-3 C₂₂H₁₈BrN₃O₇S 

Relevant articles and documents

Dihydroxyphenyl Sulfonylisoindoline Derivatives

Provided are compounds that are inhibitors of pyruvate dehydrogenase kinase (PDK), and pharmaceutically acceptable salts, hydrides and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition.

Novel 1,3-dihydro-2h-indol-2-one derivatives, method for preparing same and pharmaceutical compositions containing them

The invention relates to compounds of formula: and to solvates and/or hydrates thereof, with affinity for and selectivity towards the V1b receptors or both the V1b and V1a receptors of arginine-vasopressin. The invention also relates to a process for preparing them, to the intermediate compounds of formula (II) which are useful for preparing them, to pharmaceutical compositions containing them and to their use for preparing medicinal products.

Monomethylthio analogues of 1-(2,4,5-trimethoxyphenyl)-2-aminopropane

Regiospecific syntheses of the three monomethylthio analogues of 1-(2,4,5- trimethoxyphenyl)-2-aminopropane are described. The three isomeric amines were evaluated for potential psychotomimetic potency using the rabbit hyperthermia assay. Enantiomeric com