63682-46-2

Basic information

• Product Name: 1H-Pyrazolo[3,4-β]pyridine-3-diazonium Tetrafluoroborate(1-)
• Synonyms: 1H-Pyrazolo[3,4-β]pyridine-3-diazonium Tetrafluoroborate(1-);1H-Pyrazolo[3,4-b]pyridine-3-diazonium Tetrafluoroborate(1-)
• CAS NO: 63682-46-2
• Molecular Formula: C6H4BF3N5
• Molecular Weight: 0
• Product Categories: Aromatics Compounds;Aromatics;Heterocycles
• Mol File: 63682-46-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Solubility: DMSO
• CAS DataBase Reference: 1H-Pyrazolo[3,4-β]pyridine-3-diazonium Tetrafluoroborate(1-)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazolo[3,4-β]pyridine-3-diazonium Tetrafluoroborate(1-)(63682-46-2)
• EPA Substance Registry System: 1H-Pyrazolo[3,4-β]pyridine-3-diazonium Tetrafluoroborate(1-)(63682-46-2)

Safety Data

• Hazardous Substances Data: 63682-46-2(Hazardous Substances Data)

Usage

Description

1H-Pyrazolo[3,4-β]pyridine-3-diazonium Tetrafluoroborate(1-) is a chemical compound characterized by its unique structure and properties. It is a diazonium salt with a pyrazolo[3,4-β]pyridine core, which is a heterocyclic ring system consisting of a pyrazole fused to a pyridine. The presence of the diazonium group (-N2+) attached to the pyridine ring and the tetrafluoroborate counterion (BF4-) contribute to its reactivity and potential applications in various chemical processes.

Uses

1H-Pyrazolo[3,4-β]pyridine-3-diazonium Tetrafluoroborate(1-) is used as a synthetic intermediate in organic synthesis for the preparation of various organic compounds. Its unique structure and reactivity make it a valuable building block for the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
1H-Pyrazolo[3,4-β]pyridine-3-diazonium Tetrafluoroborate(1-) is used as a key intermediate for the synthesis of novel drug candidates with potential therapeutic applications. Its incorporation into complex molecular frameworks can lead to the development of new drugs with improved efficacy and selectivity.
Used in Agrochemical Industry:
1H-Pyrazolo[3,4-β]pyridine-3-diazonium Tetrafluoroborate(1-) is used as a precursor in the synthesis of agrochemicals, such as pesticides and herbicides. Its unique properties can contribute to the development of more effective and environmentally friendly products.
Used in Specialty Chemicals Industry:
1H-Pyrazolo[3,4-β]pyridine-3-diazonium Tetrafluoroborate(1-) is used as a versatile building block in the synthesis of specialty chemicals, including dyes, pigments, and functional materials. Its reactivity and structural features can be exploited to create new compounds with unique properties and applications.

Upstream product

• 6752-16-5 1H-pyrazolo[3,4-b]pyridin-3-amine 
• 6602-54-6 2-chloro-3-pyridinecarbonitrile 

Downstream Products

• 1470408-09-3 3-(1-(3-(1H-imidazol-1-yl)propyl)-1H-indol-3-yl)-4-(1-(3-morpholinopropyl)-1H-pyrazolo[3,4-b]pyridine-3-yl)-1-phenyl-1H-pyrrole-2,5-dione 
• 1470408-11-7 3-(1-benzyl-1H-indol-3-yl)-4-(1-(3-morpholinopropyl)-1H-pyrazolo[3,4-b]pyridine-3-yl)-1H-pyrrole-2,5-dione 
• 1470407-85-2 3-(1H-indol-3-yl)-1-phenyl-4-(1H-pyrazolo[3,4-b]pyridine-3-yl)-1H-pyrrole-2,5-dione 
• 1178564-35-6 3-(1-methyl-1H-indol-3-yl)-4-(1H-pyrazolo[3,4-b]pyridin-3-yl)-1-phenyl-1H-pyrrole-2,5-dione 
• 271-73-8 1H-Pyrazolo[3,4-b]pyridine 
• 117007-52-0 3-iodo-1H-pyrazolo[3,4-b]pyridine 
• 1178564-65-2 3-(1-methyl-1H-indol-3-yl)-4-(1-(3-morpholinopropyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-1-phenyl-1H-pyrrole-2,5-dione 
• 1470408-16-2 C₂₈H₂₃N₅O₃ 
• 1178564-40-3 3-(1-methyl-1H-indol-3-yl)-1-phenyl-4-(1-(3-(piperidin-1-yl)propyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-1H-pyrrole-2,5-dione 
• 1178564-41-4 3-(1-methyl-1H-indol-3-yl)-4-(1-(3-(1H-imidazol-1-yl)propyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-1-phenyl-1H-pyrrole-2,5-dione 
• 1178564-39-0 3-(1-(3-(dimethylamino)propyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-4-(1-methyl-1H-indol-3-yl)-1-phenyl-1H-pyrrole-2,5-dione 
• 1178564-42-5 3-(1-(2-(1H-imidazol-1-yl)ethyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-4-(1-methyl-1H-indol-3-yl)-1-phenyl-1H-pyrrole-2,5-dione 
• 1178564-43-6 3-(1-methyl-1H-indol-3-yl)-4-(1-(4-(1H-imidazol-1-yl)butyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-1-phenyl-1H-pyrrole-2,5-dione 
• 1470408-18-4 3-(1-methyl-1H-indol-3-yl)-4-(1-(2-morpholinoethyl)-1H-pyrazolo[3,4-b]pyridine-3-yl)-1-phenyl-1H-pyrrole-2,5-dione 

Relevant articles and documents

Design, synthesis and evaluation of 7-azaindazolyl-indolyl-maleimides as glycogen synthase kinase-3β (GSK-3β) inhibitors

A series of 7-azaindazolyl-indolyl-maleimides were designed, synthesized and evaluated for their GSK-3β inhibitory activity. Most compounds exhibited potent activity against GSK-3β. Among them, compounds 17a, 17b, 17g, 17i, 29a and 30 significantly reduced Aβ-induced Tau hyperphosphorylation, showin;g the inhibition of GSK-3β at the cell level. Preliminary structure-activity relationships were discussed based on the experimental data obtained.