63722-99-6

Basic information

• Product Name: 2-BROMO-1-(3,4-DIBROMO-THIOPHEN-2-YL)ETHANONE
• Synonyms: 2-BROMO-1-(3,4-DIBROMO-THIOPHEN-2-YL)ETHANONE
• CAS NO: 63722-99-6
• Molecular Formula: C6H3Br3OS
• Molecular Weight: 362.86442
• Mol File: 63722-99-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-BROMO-1-(3,4-DIBROMO-THIOPHEN-2-YL)ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-1-(3,4-DIBROMO-THIOPHEN-2-YL)ETHANONE(63722-99-6)
• EPA Substance Registry System: 2-BROMO-1-(3,4-DIBROMO-THIOPHEN-2-YL)ETHANONE(63722-99-6)

Safety Data

• Hazardous Substances Data: 63722-99-6(Hazardous Substances Data)

Upstream product

• 3141-26-2 3,4-dibromothiophene 
• 598-21-0 2-Bromoacetyl bromide 

Relevant articles and documents

Thienylhalomethylketones: Irreversible glycogen synthase kinase 3 inhibitors as useful pharmacological tools

Thienylhalomethylketones, whose chemical, biological, and pharmaceutical data are here reported, are the first irreversible inhibitors of GSK-3β described to date. Their inhibitory activity is likely related to the cysteine residue present in the ATP-binding site, which is proposed as a relevant residue for modulation of GSK-3 activity. The good cell permeability of the compounds allows them to be used in different cell models. Overall, the results presented here support the potential use of halomethylketones as pharmacological tools for the study of GSK-3β functions and suggest a new mechanism for GSK-3β inhibition that may be considered for further drug design.