63731-32-8

Basic information

• Product Name: Pyridine, 3-methyl-2-(phenylethynyl)-
• CAS NO: 63731-32-8
• Molecular Formula: C14H11N
• Molecular Weight: 193.248
• Mol File: 63731-32-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Pyridine, 3-methyl-2-(phenylethynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 3-methyl-2-(phenylethynyl)-(63731-32-8)
• EPA Substance Registry System: Pyridine, 3-methyl-2-(phenylethynyl)-(63731-32-8)

Safety Data

• Hazardous Substances Data: 63731-32-8(Hazardous Substances Data)

Upstream product

• 1003-73-2 3-picoline-N-oxide 
• 132368-30-0 N-ethoxycarbonyl-3-methylpyridinium chloride 
• 536-74-3 phenylacetylene 
• 108-99-6 3-Methylpyridine 

Downstream Products

• 56826-32-5 3-methyl-2-(phenylethynyl)pyridine 
• 1370412-49-9 2-(2,2-diphenylethyl)-3-methylpyridine 

Relevant articles and documents

A direct, copper-catalyzed functionalization of pyridines with alkynes

A one-pot, copper-catalyzed method to construct 2-alk-ynylpyridines is presented. This provides a route to access these products directly from terminal alkynes and the parent pyridine, and without prefunctionalization of the pyridine core. In addition, (Z)-alk-2-enylpyridines can be prepared via a related procedure. These reactions are used to synthesize a number of new alkynyl-and alkenyl-substituted pyridines in one pot.

A Novel Ethynylation of Pyridines by Reissert-Henze Type Reaction

Reaction of N-benzoyloxypyridinium chloride, Reissert-Henze salt, with silver acetylide gave the pyridine ethynylated selectively at 2-position.The reaction is applicable to various substituted pyridines and pyridine homologs.