63746-11-2

Basic information

• Product Name: DIISOPROPENOXYDIMETHYLSILANE
• Synonyms: DIMETHYL DI(ISOPROPENOXY) SILANE;DIISOPROPENOXYDIMETHYLSILANE;DIISOPROPENYLOXYDIMETHYLSILANE;Bis(isopropenyloxy)dimethylsilane;Silane, dimethylbis[(1-methylethenyl)oxy]-;dimethyl-bis(prop-1-en-2-yloxy)silane
• CAS NO: 63746-11-2
• Molecular Formula: C8H16O2Si
• Molecular Weight: 172.3
• Product Categories: Pharmaceutical Intermediates
• Mol File: 63746-11-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 142°C
• Appearance: /
• Density: 0,871 g/cm3
• CAS DataBase Reference: DIISOPROPENOXYDIMETHYLSILANE(CAS DataBase Reference)
• NIST Chemistry Reference: DIISOPROPENOXYDIMETHYLSILANE(63746-11-2)
• EPA Substance Registry System: DIISOPROPENOXYDIMETHYLSILANE(63746-11-2)

Safety Data

• Hazardous Substances Data: 63746-11-2(Hazardous Substances Data)

Upstream product

• 75-78-5 dimethylsilicon dichloride 
• 67-64-1 acetone 

Downstream Products

• 110-13-4 2,5-hexanedione 

Relevant articles and documents

Flexible stereoselective functionalizations of ketones through umpolung with hypervalent iodine reagents

The functionalization of carbonyl compounds in the α-position has gathered much attention as a synthetic route because of the wide biological importance of such products. Through polarity reversal, or "umpolung", we show here that typical nucleophiles, such as oxygen, nitrogen, and even carbon nucleophiles, can be used for addition reactions after tethering them to enol ethers. Our findings allow novel retrosynthetic planning and rapid assembly of structures previously accessible only by multistep sequences. A Nu approach: An efficient α-functionalization of ketones with a range of simple and useful nucleophiles is possible by using hypervalent iodine reagents (see scheme; Nu′ can be the Nu itself or a protected form of this nucleophile group).

Synthesis of silicon-functionalized dimethylsilyl enol ethers from ketones

Symmetrical dimethylsilyl bis-enol ethers are obtained in good yield by reaction of ketones with dichlorodimethylsilane in the presence of triethylamine and sodium iodide. Reaction of ketones with N,N-diethylaminodimethylchlorosilane in the presence of tr

O-SILYLATED KETENE ACETAL CHEMISTRY; DIVINYLOXYSILANE DERIVATIVES AS NOVEL AND USEFUL BIFUNCTIONAL PROTECTING AGENTS FOR H-ACIDIC MATERIALS

Novel reagents, bis(1-methoxy-2-methyl-1-propenyloxy)silanes (2a-d) have been shown to be very useful bifunctional protecting agents for various types of H-acidic materials, such as diols, dithiols, diacids and their combined materials.The reaction proceeds rapidly under mild conditions to give the corresponding silylene derivatives in almost quantitative yields.