6375-20-8Relevant articles and documents
COMPOUNDS FOR INHIBITING TNIK AND MEDICAL USES THEREOF
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Paragraph 367-369, (2019/08/29)
The present disclosure provides the compound having inhibitory property against TNIK having a specific chemical structure or its pharmaceutically acceptable salt. The present disclosure also provides a composition comprising the compound or its pharmaceutically acceptable salt. The present disclosure also provides a medical use of the compound, its salt or the composition comprising the compound or its pharmaceutically acceptable salt for treating or preventing cancer. The present disclosure also provides a method of treatment or prevention of cancer comprising administering the compound, its salt or the composition comprising the compound or its salt to a subject in need of such treatment or prevention.
Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents
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Page/Page column 297-298, (2015/11/16)
The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
2-[(Aminophenyl and amidophenyl)amino]-1-azacycloalkanes having antidiarrheal activity
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, (2008/06/13)
This invention relates to the novel use of certain aromatic substituted amidines as antidiarrheals.