6375-89-9

Basic information

• Product Name: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid methyl ester
• Synonyms: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid methyl ester;Methyl 1,2-dihydro-1-Meth...;Methyl 1,2-dihydro-1-Methyl-2-oxopyridine-5-carboxylate;Methyl 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylate;3-Pyridinecarboxylicacid, 1,6-dihydro-1-Methyl-6-oxo-, Methyl ester
• CAS NO: 6375-89-9
• Molecular Formula: C₈H₉NO₃
• Molecular Weight: 167.16196
• Mol File: 6375-89-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 138.3-139.2 °C(Solv: water (7732-18-5))
• Boiling Point: 307.4±35.0 °C(Predicted)
• Appearance: /
• Density: 1.227±0.06 g/cm3(Predicted)
• PKA: -1.28±0.62(Predicted)
• CAS DataBase Reference: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid methyl ester(6375-89-9)
• EPA Substance Registry System: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid methyl ester(6375-89-9)

Safety Data

• Hazardous Substances Data: 6375-89-9(Hazardous Substances Data)

Usage

Description

1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid methyl ester is an organic compound that belongs to the class of dihydropyridine derivatives. It is characterized by its unique chemical structure, which includes a methyl ester group and a six-membered dihydropyridine ring with a methyl group at the first position and a carbonyl group at the sixth position. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid methyl ester is known for its potential applications in various fields due to its chemical properties.

Uses

1. Used as an intermediate in the synthesis of Nudifloramide (N925500), a metabolite of Niacin (or Nicorinic acid). The expression is: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid methyl ester is used as a synthetic intermediate for the production of Nudifloramide, which is derived from Niacin.
2. Used in Pharmaceutical Industry: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid methyl ester is used as a key component in the development of new pharmaceutical compounds, particularly those targeting cardiovascular diseases. Its dihydropyridine structure makes it a promising candidate for the creation of calcium channel blockers, which are widely used in the treatment of hypertension, angina, and certain arrhythmias.
3. Used in Chemical Research: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid methyl ester can also be utilized in academic and industrial research settings to study the properties and reactivity of dihydropyridine derivatives. Its unique structure allows for the exploration of various chemical reactions and the development of new synthetic methods.
4. Used in Material Science: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid methyl ester may find applications in the development of novel materials with specific properties, such as those with potential use in sensors, optoelectronics, or as components in advanced polymers.

Upstream product

• 74-88-4 methyl iodide 
• 74357-22-5 methyl-6-ethoxynicotinate 
• 74925-37-4 ethyl 2-methoxypyridine-5-carboxylate 

Downstream Products

• 694-85-9 1-methyl-2-pyridone 
• 67-56-1 methanol 
• 3719-45-7 1-methyl-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid 
• 22540-51-8 1-methyl-6-oxopiperidine-3-carboxylic acid 
• 162330-16-7 1,6-dihydro-1-methyl-6-oxopyridine-3-carboxylic acid chloride 

Relevant articles and documents

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