6376-59-6

Basic information

• Product Name: METHYL 2-OXOVALERATE
• Synonyms: 2-oxovaleric acid methyl ester;methyl 2-oxopentanoate;3,4,5-TRIHYDROXY-N-[(4-PROPAN-2-YLPHENYL)METHYLIDENEAMINO]BENZAMIDE;2-Oxovaleric Acid Methyl Ester Methyl 2-Oxopentanoate 2-Oxopentanoic Acid Methyl Ester;METHYL 2-OXOVALERATE;2-oxopentanoic acid methyl ester
• CAS NO: 6376-59-6
• Molecular Formula: C₆H₁₀O₃
• Molecular Weight: 130.1418
• Mol File: 6376-59-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 62 °C / 12mmHg
• Appearance: /
• Refractive Index: 1.4140-1.4180
• Storage Temp.: 0-10°C
• CAS DataBase Reference: METHYL 2-OXOVALERATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-OXOVALERATE(6376-59-6)
• EPA Substance Registry System: METHYL 2-OXOVALERATE(6376-59-6)

Safety Data

• Hazardous Substances Data: 6376-59-6(Hazardous Substances Data)

Usage

General Description

Methyl 2-oxovalerate, also known as methyl pyruvate, is a chemical compound with the molecular formula C5H8O3. It is an ester of 2-oxovaleric acid and is commonly used as a flavoring agent in the food industry. Methyl 2-oxovalerate is also utilized in organic synthesis as a building block in the production of various pharmaceuticals and agrochemicals. It has a fruity, sweet aroma and is often added to perfumes and cosmetic products for its pleasant scent. Additionally, it has been studied for its potential anti-inflammatory and antioxidant properties, making it a subject of interest in the field of medical research.

InChI:InChI=1S/C6H10O3/c1-3-4-5(7)6(8)9-2/h3-4H2,1-2H3

Upstream product

• 78485-85-5 2-Trimethylsilanyloxy-pentanenitrile 
• 108740-82-5 methyl 2-hydroxyvalerate 
• 67-56-1 methanol 
• 1821-02-9 2-oxopentanoic acid 
• 553-90-2 Dimethyl oxalate 
• 80465-31-2 4-Prop-(Z)-ylidene-oxazolidine-2,5-dione 
• 72015-58-8 (Z)-2-Benzyloxycarbonylamino-pent-2-enoic acid 
• 85450-93-7 Methyl-2-(N-methylanilino)-2-butenoat 
• 74-88-4 methyl iodide 
• 95863-99-3 (Z)-2-Amino-pent-2-enoic acid methyl ester 
• 71385-54-1 (Z)-2-Amino-pent-2-enoic acid ethyl ester 
• 6395-79-5 methyl 2-cyclopropyl-2-oxoacetate 
• 186581-53-3 diazomethane 

Downstream Products

• 113366-74-8 5-ethyl-2-methylthiazole-4-carboxylic acid 
• 1821-02-9 2-oxopentanoic acid 
• 1593585-66-0 (E)-N-(1-methoxy-1-oxopentan-2-ylidene)-1-phenylmethanamine oxide 
• 1593585-84-2 (-)-(3R,5S)-methyl 2-benzyl-5-formyl-5-methyl-3-propylisoxazolidine-3-carboxylate 

Relevant articles and documents

Diastereo- and Enantioselective Synthesis of Fluorine Motifs with Two Contiguous Stereogenic Centers

The synthesis of chiral fluorine containing motifs, in particular, chiral fluorine molecules with two contiguous stereogenic centers, has attracted much interest in research due to the limited number of methods available for their preparation. Herein, we report an atom-economical and highly stereoselective synthesis of chiral fluorine molecules with two contiguous stereogenic centers via azabicyclo iridium-oxazoline-phosphine-catalyzed hydrogenation of readily available vinyl fluorides. Various aromatic, aliphatic, and heterocyclic systems with a variety of functional groups were found to be compatible with the reaction and provide the highly desirable product as single diastereomers with excellent enantioselectivities.

Polymer-supported triazenes as smart reagents for the alkylation of carboxylic acids

Starting from polystyrene, a simple four-step synthesis of polymer-supported alkyltriazenes (alkyl = Me, Et, benzyl) is described. With this synthesis, a loading capacity of 2.2 mmol g-1 can be reached. The most prominent application of these polymer-supported reagents is the rapid, highly selective and high-yielding esterification of carboxylic acids, which involves a simple mix and filter off procedure at room temperature. If stored in a refrigerator, these reagents are stable for many months and they can be recycled several times.