63866-99-9

Basic information

• Product Name: Benzenemethanol, 3-(acetyloxy)-4-methoxy-, acetate
• CAS NO: 63866-99-9
• Molecular Formula: C12H14O5
• Molecular Weight: 238.24
• Mol File: 63866-99-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 3-(acetyloxy)-4-methoxy-, acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 3-(acetyloxy)-4-methoxy-, acetate(63866-99-9)
• EPA Substance Registry System: Benzenemethanol, 3-(acetyloxy)-4-methoxy-, acetate(63866-99-9)

Safety Data

• Hazardous Substances Data: 63866-99-9(Hazardous Substances Data)

Upstream product

• 495-76-1 piperonol 
• 108-24-7 acetic anhydride 
• 108-05-4 vinyl acetate 
• 4383-06-6 3-hydroxy-4-methoxybenzyl alcohol 

Downstream Products

• 63867-05-0 3-acetoxy-4-methoxybenzyl alcohol 
• 63867-04-9 3-hydroxy-4-methoxy-benzyl acetate 

Relevant articles and documents

Twisted amides as selective acylating agents for hydroxyl groups under neutral conditions: Models for activated peptides during enzymatic acyl transfer reaction

The highly twisted amide 2 served as a selective acylating agent for diols under neutral conditions. The reaction of primary-secondary diols with 2 led to the corresponding primary alkyl monopivalates. For diols containing alcoholic and phenolic hydroxyl groups, alcoholic hydroxyl groups were selectively acylated under neutral conditions, whereas, the opposite selectivity was observed under basic conditions, similar to the cases using acyl halides or acid anhydrides. Although 1 and 3 were unreactive to alcohols, 5-10 having substituent groups at C-4 were reactive to alcohols to give the corresponding acetates or benzoates.

CONVERSION OF METHYLENEDIOXYBENZENE DERIVATIVES INTO 2-METHOXYPHENOL DERIVATIVES

Methylenedioxybenzene derivatives are reductively cleft with diisobutylaluminum hydride to give 2-methoxyphenol derivatives.Concurrent hydroalumination occures when a substrate contains an olefinic bond in a side chain.