63884-78-6

Basic information

• Product Name: 4'-AMINOOCTANOPHENONE
• Synonyms: 4'-AMINOOCTANOPHENONE;HEPTYL 4-AMINOPHENYL KETONE;4-n-octanoylaniline;4-aminooctoylphenone;4''-AMINOOCTANOPHENONE,97.0%+(GC)(T)
• CAS NO: 63884-78-6
• Molecular Formula: C₁₄H₂₁NO
• Molecular Weight: 219.32264
• Mol File: 63884-78-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 105 °C
• Boiling Point: 371.4°C at 760 mmHg
• Flash Point: 178.4°C
• Appearance: /
• Density: 0.986g/cm³
• Vapor Pressure: 1.03E-05mmHg at 25°C
• Refractive Index: 1.526
• Solubility: soluble in Methanol
• CAS DataBase Reference: 4'-AMINOOCTANOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-AMINOOCTANOPHENONE(63884-78-6)
• EPA Substance Registry System: 4'-AMINOOCTANOPHENONE(63884-78-6)

Safety Data

• RTECS: EY4375000
• Hazardous Substances Data: 63884-78-6(Hazardous Substances Data)

Usage

General Description

4'-Aminooctanophenone, also known as 4'-Aminooctanophenone, is a chemical compound with the molecular formula C8H15NO. It is a yellow liquid that is insoluble in water but soluble in organic solvents. This chemical is used as an intermediate in the production of pharmaceuticals, dyes, and other organic compounds. It is also used in the synthesis of other compounds and as a reagent in various chemical reactions. 4'-Aminooctanophenone has the potential for various applications in the pharmaceutical and chemical industries due to its unique properties and versatility. Overall, this compound is an important building block for the synthesis of a wide range of organic compounds and plays a crucial role in the production of various products.

InChI:InChI=1/C14H21NO/c1-2-3-4-5-6-7-14(16)12-8-10-13(15)11-9-12/h8-11H,2-7,15H2,1H3

Upstream product

• 99-92-3 p-aminobenzophenone 
• 111-27-3 hexan-1-ol 
• 101255-33-8 acetic acid-(4-octanoyl-anilide) 
• 7295-52-5 1-(4-chlorophenyl)-5,5-dimethylhexan-1-one 
• 111-64-8 n-octanoic acid chloride 
• 103-84-4 Acetanilid 
• 108-90-7 chlorobenzene 

Downstream Products

• 101438-36-2 N-methyl-N'-(4-octanoyl-phenyl)-thiourea 
• 16245-79-7 4-octylaniline 

Relevant articles and documents

Synthesis and methemoglobinemia-inducing properties of analogues of para-aminopropiophenone designed as humane rodenticides

A number of structural analogues of the known toxicant para- aminopropiophenone (PAPP) have been prepared and evaluated for their capacity to induce methemoglobinemia - with a view to their possible application as humane pest control agents. It was found that an optimal lipophilicity for the formation of methemoglobin (metHb) in vitro existed for alkyl analogues of PAPP (aminophenones 1-20; compound 6 metHb% = 74.1 ± 2). Besides lipophilicity, this structural sub-class suggested there were certain structural requirements for activity, with both branched (10-16) and cyclic (17-20) alkyl analogues exhibiting inferior in vitro metHb induction. Of the four candidates (compounds 4, 6, 13 and 23) evaluated in vivo, 4 exhibited the greatest toxicity. In parallel, aminophenone bioisosteres, including oximes 30-32, sulfoxide 33, sulfone 34 and sulfonamides 35-36, were found to be inferior metHb inducers to lead ketone 4. Closer examination of Hammett substituent constants suggests that a particular combination of the field and resonance parameters may be significant with respect to the redox mechanisms behind PAPPs metHb toxicity.