63887-20-7

Basic information

• Product Name: 2-amino-4-chloro-N-cyclopropylbenzamide
• Synonyms: 2-amino-4-chloro-N-cyclopropylbenzamide
• CAS NO: 63887-20-7
• Molecular Formula: C10H11ClN2O
• Molecular Weight: 210.6601
• Mol File: 63887-20-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 395.1 °C at 760 mmHg
• Flash Point: 192.8 °C
• Appearance: /
• Density: 1.34 g/cm³
• Vapor Pressure: 1.88E-06mmHg at 25°C
• Refractive Index: 1.623
• PKA: 14.06±0.20(Predicted)
• CAS DataBase Reference: 2-amino-4-chloro-N-cyclopropylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-4-chloro-N-cyclopropylbenzamide(63887-20-7)
• EPA Substance Registry System: 2-amino-4-chloro-N-cyclopropylbenzamide(63887-20-7)

Safety Data

• Hazardous Substances Data: 63887-20-7(Hazardous Substances Data)

Usage

Description

2-amino-4-chloro-N-cyclopropylbenzamide is a chemical compound with the molecular formula C11H11ClN2O. It is a potent and selective inhibitor of the enzyme inosine monophosphate dehydrogenase (IMPDH), which plays a crucial role in the de novo synthesis of guanine nucleotides. 2-amino-4-chloro-N-cyclopropylbenzamide has shown potential therapeutic applications in various medical fields, including the treatment of autoimmune diseases, organ transplantation, and certain types of cancer. Its ability to inhibit IMPDH makes it a promising candidate for the development of novel pharmaceutical drugs. However, further research is necessary to fully understand its mechanisms of action and potential clinical applications.

Uses

Used in Pharmaceutical Industry:
2-amino-4-chloro-N-cyclopropylbenzamide is used as a therapeutic agent for the treatment of autoimmune diseases, organ transplantation, and certain types of cancer. Its inhibitory effects on IMPDH make it a promising candidate for the development of novel pharmaceutical drugs.
Used in Autoimmune Disease Treatment:
2-amino-4-chloro-N-cyclopropylbenzamide is used as a treatment for autoimmune diseases, as its inhibition of IMPDH can help regulate the immune system and reduce inflammation.
Used in Organ Transplantation:
2-amino-4-chloro-N-cyclopropylbenzamide is used as an immunosuppressive agent in organ transplantation to prevent organ rejection and promote successful transplantation outcomes.
Used in Cancer Treatment:
2-amino-4-chloro-N-cyclopropylbenzamide is used as a potential cancer treatment, as its inhibitory effects on IMPDH can disrupt the rapid cell growth and proliferation associated with cancer cells. Further research is needed to explore its full potential in this area.

InChI:InChI=1/C10H11ClN2O/c11-6-1-4-8(9(12)5-6)10(14)13-7-2-3-7/h1,4-5,7H,2-3,12H2,(H,13,14)